Micro-and nano-to millimeter-scale magnetic matrix materials have gained widespread application due to their exceptional magnetic properties and favorable cost-effectiveness.With the rapid progress in condensed matter...Micro-and nano-to millimeter-scale magnetic matrix materials have gained widespread application due to their exceptional magnetic properties and favorable cost-effectiveness.With the rapid progress in condensed matter physics,materials science,and mineral separation technologies,these materials are now poised for new opportunities in theoretical research and development.This review provides a comprehensive analysis of these matrices,encompassing their structure,size,shape,composition,properties,and multifaceted applications.These materials,primarily composed of alloys of transition state metasl such as iron(Fe),cobalt(Co),titanium(Ti),and nickel(Ni),exhibit unique attributes like high magnetization rates,low eleastic modulus,and high saturation magnetic field strengths.Furthermore,the studies also delve into the complex mechanical interactions involved in the separation of magnetic particles using magnetic separator matrices,including magnetic,gravitational,centrifugal,and van der Waals forces.The review outlines how size and shape effects influence the magnetic behavior of matrices,offering new perspectives for innovative applications of magnetic matrices in various domains of materials science and magnetic separation.展开更多
目的预测疥螨猪变种转录组中过敏原蛋白,对Sar s 14.3过敏原蛋白进行生物特性分析、原核表达并建立间接ELISA诊断方法。方法利用转录组测序(RNA-Seq)及BLAST、ProtParam、I-TASSER和COMPARE等软件和数据库对疥螨猪变种转录组中的过敏原...目的预测疥螨猪变种转录组中过敏原蛋白,对Sar s 14.3过敏原蛋白进行生物特性分析、原核表达并建立间接ELISA诊断方法。方法利用转录组测序(RNA-Seq)及BLAST、ProtParam、I-TASSER和COMPARE等软件和数据库对疥螨猪变种转录组中的过敏原组分进行预测并对疥螨Sar s 14.3过敏原蛋白序列进行理化性质分析、结构分析、同源性分析和间接ELISA诊断方法的建立。结果在疥螨猪变种的18980个转录本中共预测出390条过敏原序列,且随机匹配可能性值(E-value)为0的序列有28条。Sar s 14.3过敏原蛋白的理论相对分子质量为38 kDa,蛋白较稳定,为亲水性蛋白;二级结构以无规卷曲和β-折叠为主,其氨基酸序列与疥螨其他变种主要过敏原组分14蛋白序列相似性不低于99.76%,而与尘螨属螨虫的相似性最高为73.08%,与现行的形态学分类系统一致。所建立的间接ELISA诊断方法的最佳包被抗原浓度为2μg/mL,血清最佳稀释倍数是1∶400。结论本试验成功预测了疥螨猪变种转录组中的过敏原序列并克隆、表达了疥螨猪变种Sar s 14.3蛋白,初步预测了其分子特征,并以该过敏原蛋白为基础成功建立了一种快速的间接ELISA检测方法,可用于疥螨病的初步诊断和流行病学调查。展开更多
Bridges crossing active faults are more likely to suffer serious damage or even collapse due to the wreck capabilities of near-fault pulses and surface ruptures under earthquakes.Taking a high-speed railway simply-sup...Bridges crossing active faults are more likely to suffer serious damage or even collapse due to the wreck capabilities of near-fault pulses and surface ruptures under earthquakes.Taking a high-speed railway simply-supported girder bridge with eight spans crossing an active strike-slip fault as the research object,a refined coupling dynamic model of the high-speed train-CRTS III slab ballastless track-bridge system was established based on ABAQUS.The rationality of the established model was thoroughly discussed.The horizontal ground motions in a fault rupture zone were simulated and transient dynamic analyses of the high-speed train-track-bridge coupling system under 3-dimensional seismic excitations were subsequently performed.The safe running speed limits of a high-speed train under different earthquake levels(frequent occurrence,design and rare occurrence)were assessed based on wheel-rail dynamic(lateral wheel-rail force,derailment coefficient and wheel-load reduction rate)and rail deformation(rail dislocation,parallel turning angle and turning angle)indicators.Parameter optimization was then investigated in terms of the rail fastener stiffness and isolation layer friction coefficient.Results of the wheel-rail dynamic indicators demonstrate the safe running speed limits for the high-speed train to be approximately 200 km/h and 80 km/h under frequent and design earthquakes,while the train is unable to run safely under rare earthquakes.In addition,the rail deformations under frequent,design and rare earthquakes meet the safe running requirements of the high-speed train for the speeds of 250,100 and 50 km/h,respectively.The speed limits determined for the wheel-rail dynamic indicators are lower due to the complex coupling effect of the train-track-bridge system under track irregularity.The running safety of the train was improved by increasing the fastener stiffness and isolation layer friction coefficient.At the rail fastener lateral stiffness of 60 kN/mm and isolation layer friction coefficients of 0.9 and 0.8,respectively,the safe running speed limits of the high-speed train increased to 250 km/h and 100 km/h under frequent and design earthquakes,respectively.展开更多
基金Project(52174245)supported by the National Natural Science Foundation of ChinaProject(2021J01640)supported by the Natural Science Foundation of Fujian Province,ChinaProject(BGRIMM-KJSKL2022-03)supported by Open Foundation of the State Key Laboratory of Mineral Processing,China。
文摘Micro-and nano-to millimeter-scale magnetic matrix materials have gained widespread application due to their exceptional magnetic properties and favorable cost-effectiveness.With the rapid progress in condensed matter physics,materials science,and mineral separation technologies,these materials are now poised for new opportunities in theoretical research and development.This review provides a comprehensive analysis of these matrices,encompassing their structure,size,shape,composition,properties,and multifaceted applications.These materials,primarily composed of alloys of transition state metasl such as iron(Fe),cobalt(Co),titanium(Ti),and nickel(Ni),exhibit unique attributes like high magnetization rates,low eleastic modulus,and high saturation magnetic field strengths.Furthermore,the studies also delve into the complex mechanical interactions involved in the separation of magnetic particles using magnetic separator matrices,including magnetic,gravitational,centrifugal,and van der Waals forces.The review outlines how size and shape effects influence the magnetic behavior of matrices,offering new perspectives for innovative applications of magnetic matrices in various domains of materials science and magnetic separation.
文摘目的预测疥螨猪变种转录组中过敏原蛋白,对Sar s 14.3过敏原蛋白进行生物特性分析、原核表达并建立间接ELISA诊断方法。方法利用转录组测序(RNA-Seq)及BLAST、ProtParam、I-TASSER和COMPARE等软件和数据库对疥螨猪变种转录组中的过敏原组分进行预测并对疥螨Sar s 14.3过敏原蛋白序列进行理化性质分析、结构分析、同源性分析和间接ELISA诊断方法的建立。结果在疥螨猪变种的18980个转录本中共预测出390条过敏原序列,且随机匹配可能性值(E-value)为0的序列有28条。Sar s 14.3过敏原蛋白的理论相对分子质量为38 kDa,蛋白较稳定,为亲水性蛋白;二级结构以无规卷曲和β-折叠为主,其氨基酸序列与疥螨其他变种主要过敏原组分14蛋白序列相似性不低于99.76%,而与尘螨属螨虫的相似性最高为73.08%,与现行的形态学分类系统一致。所建立的间接ELISA诊断方法的最佳包被抗原浓度为2μg/mL,血清最佳稀释倍数是1∶400。结论本试验成功预测了疥螨猪变种转录组中的过敏原序列并克隆、表达了疥螨猪变种Sar s 14.3蛋白,初步预测了其分子特征,并以该过敏原蛋白为基础成功建立了一种快速的间接ELISA检测方法,可用于疥螨病的初步诊断和流行病学调查。
基金Project(51378050) supported by the National Natural Science Foundation of ChinaProject(B13002) supported by the “111” Project,China+2 种基金Project (8192035) supported by the Beijing Municipal Natural Science Foundation,ChinaProject(P2019G002) supported by the Science and Technology Research and Development Program of China RailwayProject(2019YJ193) supported by the State Key Laboratory for Track Technology of High-speed Railway,China。
文摘Bridges crossing active faults are more likely to suffer serious damage or even collapse due to the wreck capabilities of near-fault pulses and surface ruptures under earthquakes.Taking a high-speed railway simply-supported girder bridge with eight spans crossing an active strike-slip fault as the research object,a refined coupling dynamic model of the high-speed train-CRTS III slab ballastless track-bridge system was established based on ABAQUS.The rationality of the established model was thoroughly discussed.The horizontal ground motions in a fault rupture zone were simulated and transient dynamic analyses of the high-speed train-track-bridge coupling system under 3-dimensional seismic excitations were subsequently performed.The safe running speed limits of a high-speed train under different earthquake levels(frequent occurrence,design and rare occurrence)were assessed based on wheel-rail dynamic(lateral wheel-rail force,derailment coefficient and wheel-load reduction rate)and rail deformation(rail dislocation,parallel turning angle and turning angle)indicators.Parameter optimization was then investigated in terms of the rail fastener stiffness and isolation layer friction coefficient.Results of the wheel-rail dynamic indicators demonstrate the safe running speed limits for the high-speed train to be approximately 200 km/h and 80 km/h under frequent and design earthquakes,while the train is unable to run safely under rare earthquakes.In addition,the rail deformations under frequent,design and rare earthquakes meet the safe running requirements of the high-speed train for the speeds of 250,100 and 50 km/h,respectively.The speed limits determined for the wheel-rail dynamic indicators are lower due to the complex coupling effect of the train-track-bridge system under track irregularity.The running safety of the train was improved by increasing the fastener stiffness and isolation layer friction coefficient.At the rail fastener lateral stiffness of 60 kN/mm and isolation layer friction coefficients of 0.9 and 0.8,respectively,the safe running speed limits of the high-speed train increased to 250 km/h and 100 km/h under frequent and design earthquakes,respectively.
