随着物联网技术的飞速发展,射频识别(Radio Frequency Identification,RFID)系统因具有非接触、快速识别等优点而成为了解决物联网问题的首选方案。RFID网络规划问题要考虑多个目标,被证明是多目标优化的问题。群体智能(Swarm Intellige...随着物联网技术的飞速发展,射频识别(Radio Frequency Identification,RFID)系统因具有非接触、快速识别等优点而成为了解决物联网问题的首选方案。RFID网络规划问题要考虑多个目标,被证明是多目标优化的问题。群体智能(Swarm Intelligence,SI)算法在解决多目标优化问题方面得到了广泛的关注。文中提出了一种改进型灰狼算法(Improved Grey Wolf Optimizer,IGWO),利用高斯变异算子和惯性常量策略来实现RFID网络规划。通过建立优化模型,在满足标签100%覆盖率、部署更少的阅读器、避免信号干扰、消耗更少的功率4个目标的基础上,将所提算法与粒子群算法(Particle Swarm Optimization,PSO)、遗传算法(Genetic Algorithm,GA)、帝王蝶算法(Monarch Butterfly Algorithm,MMBO)进行了对比分析。实验结果表明,灰狼算法在RFID网络规划时表现更优异,在相同的实验环境下,相较于其他算法,IGWO的适应度值比GA提高了20.2%,比PSO提高了13.5%,比MMBO提高了9.66%;并且覆盖的标签数更多,可以更有效地求出最优化方案。展开更多
The improved cross-correlation algorithm for the strain demodulation of Vernier-effect-based optical fiber sensor(VE-OFS)is proposed in this article.The algorithm identifies the most similar spectrum to the measured o...The improved cross-correlation algorithm for the strain demodulation of Vernier-effect-based optical fiber sensor(VE-OFS)is proposed in this article.The algorithm identifies the most similar spectrum to the measured one from the database of the collected spectra by employing the cross-correlation operation,subsequently deriving the predicted value via weighted calculation.As the algorithm uses the complete information in the measured raw spectrum,more accurate results and larger measurement range can be obtained.Additionally,the improved cross-correlation algorithm also has the potential to improve the measurement speed compared to current standards due to the possibility for the collection using low sampling rate.This work presents an important algorithm towards a simpler,faster way to improve the demodulation performance of VE-OFS.展开更多
文摘子宫内膜癌(endometrial cancer,EC)是最常见的妇科恶性肿瘤,其发病率逐年上升.近年来,随着靶向治疗在临床上的广泛应用,探索与研究新靶点成为实现子宫内膜癌精准治疗的重要一环.越来越多的研究发现,E3泛素连接酶斑点型锌指结构蛋白(speckle-type POZ protein,SPOP)对子宫内膜癌的发生发展起到了重要的抑制作用.本文将介绍泛素-蛋白酶体系统(ubiquitin-proteasome system,UPS)SPOP的结构、功能,探讨调控和影响SPOP的因素以及SPOP在子宫内膜癌中的突变情况和相关底物.重点围绕SPOP的下游三条信号通路:雌激素受体α(estrogen receptor-α,ERα)介导的信号通路、溴结构域和端外蛋白(bromodomain and extraterminal protein,BET)通路及锌指和BTB结构域蛋白3(zinc finger and BTB domain-containing protein 3,ZBTB3)通路,对它们抑制子宫内膜癌发生发展的分子机制进行总结,以期为SPOP作为新的子宫内膜癌治疗靶点提供理论基础.
文摘The improved cross-correlation algorithm for the strain demodulation of Vernier-effect-based optical fiber sensor(VE-OFS)is proposed in this article.The algorithm identifies the most similar spectrum to the measured one from the database of the collected spectra by employing the cross-correlation operation,subsequently deriving the predicted value via weighted calculation.As the algorithm uses the complete information in the measured raw spectrum,more accurate results and larger measurement range can be obtained.Additionally,the improved cross-correlation algorithm also has the potential to improve the measurement speed compared to current standards due to the possibility for the collection using low sampling rate.This work presents an important algorithm towards a simpler,faster way to improve the demodulation performance of VE-OFS.
