The ring opening reaction of methyloxirane(PO) in hydrochloric acid(HCl) has been studied by NMR and gas chromatography. It is found that under experimental conditions α and β chloropropanol in the reaction products...The ring opening reaction of methyloxirane(PO) in hydrochloric acid(HCl) has been studied by NMR and gas chromatography. It is found that under experimental conditions α and β chloropropanol in the reaction products were in a molar ratio of about 2∶1. The ratio was almost constant when the molar ratio of c PO ∶c HCl ranged from 1∶0 3 to 1∶1 4, at reaction temperature from 0 to 65 ℃ and reaction time from 1 to 60 min. It is proposed that the addition reaction of HCl should follow an S N2 mechanism, and that which carbon atom would be attacked by nucleophilic agent Cl - is decided by space factor and not by the electron factor.展开更多
文摘The ring opening reaction of methyloxirane(PO) in hydrochloric acid(HCl) has been studied by NMR and gas chromatography. It is found that under experimental conditions α and β chloropropanol in the reaction products were in a molar ratio of about 2∶1. The ratio was almost constant when the molar ratio of c PO ∶c HCl ranged from 1∶0 3 to 1∶1 4, at reaction temperature from 0 to 65 ℃ and reaction time from 1 to 60 min. It is proposed that the addition reaction of HCl should follow an S N2 mechanism, and that which carbon atom would be attacked by nucleophilic agent Cl - is decided by space factor and not by the electron factor.
