A model of incomplete cerebral ischemia caused by bilateral ligation of the commoncarotid arteries in rats was used to examine the effect of naomaikang on the relief of cellulardamage following cerbral ischemia.Cellul...A model of incomplete cerebral ischemia caused by bilateral ligation of the commoncarotid arteries in rats was used to examine the effect of naomaikang on the relief of cellulardamage following cerbral ischemia.Cellular damage and the formation of peroxidation productswere reduced in rats pretreated with naomaikang.It has been suggested that the free radical re-action involved with tissue damage,particularly with the injury of neurons in cerebral ischemia.The results showed that the degree of lipid peroxidation can be lowered by the pretreatmentwith naomaikang in the model of incomplete cerebral ischemia,and suggested that this drug isbeneficial to the recovery of cerebral ischemia in humans.展开更多
The effects of taurine on rat erythrocyte deformability and membrane stabilization were studied in vitro.The results demonstrated that taurine(5～25 mmol·L-1) could markedly increase erythrocyte deformability,sta...The effects of taurine on rat erythrocyte deformability and membrane stabilization were studied in vitro.The results demonstrated that taurine(5～25 mmol·L-1) could markedly increase erythrocyte deformability,stabilize cell membrane and possess protective effects on the red blood cells in rats.Taurine could also enhance the activity of superoxide dismutase(SOD) and suppress the rise of malondialdehye(MDA) level of erythrocyte. Except for MDA content,these effects of taurine showed a concentration-dependent relation. The anti-free radical action was considered to be one of the mechanisms of cell protective effect of taurine.展开更多
文摘A model of incomplete cerebral ischemia caused by bilateral ligation of the commoncarotid arteries in rats was used to examine the effect of naomaikang on the relief of cellulardamage following cerbral ischemia.Cellular damage and the formation of peroxidation productswere reduced in rats pretreated with naomaikang.It has been suggested that the free radical re-action involved with tissue damage,particularly with the injury of neurons in cerebral ischemia.The results showed that the degree of lipid peroxidation can be lowered by the pretreatmentwith naomaikang in the model of incomplete cerebral ischemia,and suggested that this drug isbeneficial to the recovery of cerebral ischemia in humans.
文摘The effects of taurine on rat erythrocyte deformability and membrane stabilization were studied in vitro.The results demonstrated that taurine(5～25 mmol·L-1) could markedly increase erythrocyte deformability,stabilize cell membrane and possess protective effects on the red blood cells in rats.Taurine could also enhance the activity of superoxide dismutase(SOD) and suppress the rise of malondialdehye(MDA) level of erythrocyte. Except for MDA content,these effects of taurine showed a concentration-dependent relation. The anti-free radical action was considered to be one of the mechanisms of cell protective effect of taurine.
