The effect of lipopolysaccharide(LPS)on the production of NO in primary cultures of rat intestinal mucosa microvascular endothelial cells(RIMEC)was investigated . RIMEC weve in culture exposed to the inflammatory cyto...The effect of lipopolysaccharide(LPS)on the production of NO in primary cultures of rat intestinal mucosa microvascular endothelial cells(RIMEC)was investigated . RIMEC weve in culture exposed to the inflammatory cytokine LPS. Stable NO production, which accumulated in the culture medium without LPS in a linear way for 24 h . LPS induced NO production in RIMEC in a time-dependent manner. These data indicate that LPS triggered endothelial cells activation, the production of NO was enhanced.展开更多
文摘The effect of lipopolysaccharide(LPS)on the production of NO in primary cultures of rat intestinal mucosa microvascular endothelial cells(RIMEC)was investigated . RIMEC weve in culture exposed to the inflammatory cytokine LPS. Stable NO production, which accumulated in the culture medium without LPS in a linear way for 24 h . LPS induced NO production in RIMEC in a time-dependent manner. These data indicate that LPS triggered endothelial cells activation, the production of NO was enhanced.
