摘要
慢性肾脏病发病率逐年提高,随着透析技术的发展,维持性血液透析患者显著增加,研究证实,心血管疾病是维持性血液透析患者死亡的重要原因,心血管疾病给维持性血液透析患者带来极大威胁,积极寻找心血管疾病发生的危险因素至关重要.传统危险因素包括血压及脂质代谢异常,血压过低会增加病死率.非传统危险因素包括贫血及营养不良-炎性反应-动脉粥样硬化综合征、钙磷代谢紊乱.贫血是心血管事件独立危险因素,而维持性血液透析患者容易进入慢性微炎性反应状态,这种慢性炎性反应可通过多种途径促进动脉硬化的发生,高磷血症是慢性肾脏病患者死亡的独立危险因素.因此合理控制血压,积极改善贫血及炎性反应状态,调节钙磷代谢,是延缓或降低维持性血液透析患者心血管事件的重要措施.
Chronic kidney disease incidence increased year by year, with the development of dialysis, hemodialysis patients increased significantly, the research confirmed that cardiovascular disease is an important cause of death in patients with maintenance hemodialysis, cardiovascular disease has brought great threaten to the hemodialysis patients, actively looking for important risk factors of occurrence of cardiovascular diseases. Traditional risk factors, including blood pressure and lipid metabolism, blood pressure is too low will increase the mortality rate. Non traditional risk factors include anemia, malnutrion- inflammatory- atherosclerosis- syndrome, calcium and phosphorus metabolism disorders. Anemia is an independent risk factor for cardiovascular events, and hemodialysis patients easily into the chronic inflammatory state, the chronic inflammatory reaction through a variety of ways to promote atherosclerosis, hyperphosphatemia is independent risk factors for death in patients with chronic kidney disease. Therefore, reasonable control of blood pressure, and actively improve the anemia and inflammation, regulate calcium and phosphorus metabolism, is the important measure to delay or reduce the cardiovascular events in maintenance hemodialysis patients.
出处
《中国医师进修杂志》
2016年第z1期-,共5页
Chinese Journal of Postgraduates of Medicine
关键词
肾透析
心血管疾病
危险因素
综述
Renal dialysis
Cardiovascular diseases
Risk factors
Review
