摘要
<strong>Background:</strong> <span style="font-family:;" "=""><span style="font-family:Verdana;">Endometriosis </span><span style="font-family:Verdana;">is enigmatic</span></span><span style="font-family:;" "=""> <span style="font-family:Verdana;">clinical</span><span style="font-family:Verdana;"> entity </span><span style="font-family:Verdana;">which is</span><span style="font-family:Verdana;"> described as the location of the endometrial tissue external of the uterine cavity. Endometriosis constitutes a serious health issue due to its high affliction of 10% of reproductive women. With limited resources in Africa, it is essential to assess whether </span><span style="font-family:Verdana;">diagnosis</span><span style="font-family:Verdana;"> of endometriosis by laparoscopic visualization can be used as a substitute for histology. </span><b><span style="font-family:Verdana;">Objective: </span></b><span style="font-family:Verdana;">To correlate the diagnosis of endometriosis by laparoscopic visualization and the histological confirmation of the biopsy taken. </span><b><span style="font-family:Verdana;">Methods: </span></b></span><span style="font-family:;" "=""><span style="font-family:Verdana;">A</span><b> </b></span><span style="font-family:;" "=""><span style="font-family:Verdana;">prospective cross sectional study with a sample size of 443 was undertaken in the diagnosis of endometriosis among Africans in Nairobi, Kenya from March 2019 to March 2021. Women undergoing laparoscopy were screened for endometriosis by visualization and a biopsy was taken for histopathology. Diagnosis of endometriosis by visualization was correlated with </span><span style="font-family:Verdana;">histological</span><span style="font-family:Verdana;"> confirmed endometriosis. </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> Women with a diagnosis of endometriosis through laparoscopic visualization were found to be 77 (17.4%) and 30 (6.8%) had positive histology for endometriosis. Laparoscopic visualization diagnosis had a low positive predictive value of 39%. </span><b><span style="font-family:Verdana;">Conclusion: </span></b><span style="font-family:Verdana;">Laparoscopic visualization diagnosis had a low positive predictive value of 39% and this d</span></span><span style="font-family:Verdana;">id</span><span style="font-family:Verdana;"> not correlate with histopathologic diagnosis. It </span><span style="font-family:Verdana;">is </span><span style="font-family:;" "=""><span style="font-family:Verdana;">essential to perform </span><span style="font-family:Verdana;">biopsy</span><span style="font-family:Verdana;"> with histopathology for the confirmation of endometriosis.</span></span>
<strong>Background:</strong> <span style="font-family:;" "=""><span style="font-family:Verdana;">Endometriosis </span><span style="font-family:Verdana;">is enigmatic</span></span><span style="font-family:;" "=""> <span style="font-family:Verdana;">clinical</span><span style="font-family:Verdana;"> entity </span><span style="font-family:Verdana;">which is</span><span style="font-family:Verdana;"> described as the location of the endometrial tissue external of the uterine cavity. Endometriosis constitutes a serious health issue due to its high affliction of 10% of reproductive women. With limited resources in Africa, it is essential to assess whether </span><span style="font-family:Verdana;">diagnosis</span><span style="font-family:Verdana;"> of endometriosis by laparoscopic visualization can be used as a substitute for histology. </span><b><span style="font-family:Verdana;">Objective: </span></b><span style="font-family:Verdana;">To correlate the diagnosis of endometriosis by laparoscopic visualization and the histological confirmation of the biopsy taken. </span><b><span style="font-family:Verdana;">Methods: </span></b></span><span style="font-family:;" "=""><span style="font-family:Verdana;">A</span><b> </b></span><span style="font-family:;" "=""><span style="font-family:Verdana;">prospective cross sectional study with a sample size of 443 was undertaken in the diagnosis of endometriosis among Africans in Nairobi, Kenya from March 2019 to March 2021. Women undergoing laparoscopy were screened for endometriosis by visualization and a biopsy was taken for histopathology. Diagnosis of endometriosis by visualization was correlated with </span><span style="font-family:Verdana;">histological</span><span style="font-family:Verdana;"> confirmed endometriosis. </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> Women with a diagnosis of endometriosis through laparoscopic visualization were found to be 77 (17.4%) and 30 (6.8%) had positive histology for endometriosis. Laparoscopic visualization diagnosis had a low positive predictive value of 39%. </span><b><span style="font-family:Verdana;">Conclusion: </span></b><span style="font-family:Verdana;">Laparoscopic visualization diagnosis had a low positive predictive value of 39% and this d</span></span><span style="font-family:Verdana;">id</span><span style="font-family:Verdana;"> not correlate with histopathologic diagnosis. It </span><span style="font-family:Verdana;">is </span><span style="font-family:;" "=""><span style="font-family:Verdana;">essential to perform </span><span style="font-family:Verdana;">biopsy</span><span style="font-family:Verdana;"> with histopathology for the confirmation of endometriosis.</span></span>
作者
J. Wanyoike Gichuhi
Julius Ogengo
Peter Gichangi
J. Wanyoike Gichuhi;Julius Ogengo;Peter Gichangi(Department of Obstetrics & Gynaecology, University of Nairobi, Nairobi, Kenya;Department of Anatomy, University of Nairobi, Nairobi, Kenya)
