摘要
肥胖症已演变为全球性公共卫生危机,其患病率与相关死亡率呈持续攀升态势。流行病学数据显示,随着代谢异常人群基数扩大,肥胖相关健康危害的严重性日益凸显,其防控已被列为全球公共卫生优先事项。当前现代医学主要依赖化学药物干预,但面临药物不良反应发生率高、患者长期耐受性差等治疗瓶颈。在此背景下,中医药多靶点调控、整体调节及个体化诊疗的优势尤为突出,其“调枢通腑”的治则与“形神共调”的干预模式为肥胖症管理提供了创新路径。本文通过系统梳理中医治疗肥胖症的临床循证证据及分子药理学机制研究进展,重点解析中药复方、针灸推拿及导引功法等特色疗法的代谢调控网络,以期为中医药防治肥胖症的研究体系优化提供理论参考和实践指引。Obesity has evolved into a global public health crisis, with its prevalence and associated mortality rates continuing to rise. Epidemiologic data show that with the expansion of the population base of metabolic abnormalities, the severity of obesity-related health hazards has become more and more prominent, and its prevention and control has been listed as a global public health priority. Currently, modern medicine mainly relies on chemical drug interventions, but faces treatment bottlenecks such as high incidence of adverse drug reactions and poor long-term tolerance of patients. In this context, the advantages of Chinese medicine in multi-target regulation, overall adjustment and individualized diagnosis and treatment are particularly prominent, and its treatment principle of “regulating the central and internal organs” and the intervention mode of “form and spirit co-adjustment” provide innovative paths for the management of obesity. In this paper, we systematically sort out the clinical evidence and molecular pharmacology mechanism of obesity treatment in Chinese medicine, and focus on analyzing the metabolic regulation network of Chinese medicine compound, acupuncture, massage and guiding gongfu, in order to provide theoretical references and practical guidelines for the optimization of the research system of Chinese medicine to prevent and treat obesity.
出处
《中医学》
2025年第4期1709-1715,共7页
Traditional Chinese Medicine
