摘要
以介孔分子筛MCM-41固载磷钨酸为催化剂,对苯并三氮唑与查尔酮进行了氮杂迈克加成的催化研究。经过条件筛选,发现MCM-41中的磷钨酸负载量对该反应体系有很大的影响,其中50 wt%的磷钨酸负载量更有利于反应的进行,产率可达98%。通过NMR对产物结构进行了表征,并且催化剂具有一定的回收再利用效果。
In this paper, mesoporous siliceous material MCM-41 supported H3PW12O40 (PW) could act as an efficient catalyst for the aza-Michael addition reaction of chalcone with benzotriazole. As can be seen from a serial of reaction conditions, the ratio of PW and MCM-41 plays a critical role in the reaction, and the best catalyzed result was achieved when using 50 wt% PW/MCM-41, and the yield was up to 98%. All the products were confirmed by NMR techniques. Moreover, the catalyst was also found to exhibit better recyclability.
出处
《有机化学研究》
2017年第2期107-113,共7页
Journal of Organic Chemistry Research
基金
国家自然科学基金(Nos. 21362036, 21161026)。
作者简介
通讯作者:惠永海.
