摘要
葶苈大枣泻肺汤源于东汉张仲景《金匮要略》,由葶苈子和大枣组成,具有泻肺行水、下气平喘的功效。用于肺痈初期,风热邪毒壅滞于肺,邪实气闭之证。被历代医家推崇并沿用至今,通过加减药味扩大了该方的应用范围,现代临床多用于治疗肺癌、肺炎、哮喘、心力衰竭、胸腔积液等肺系、心脏类疾病。笔者从葶苈大枣泻肺汤的源流考证与方义衍变、制法及剂量考证、物质基础研究、现代药理学研究、现代临床应用等方面进行系统阐述,为该方进一步的研究开发提供理论依据,并为其制剂的临床定位提供文献参考。
Tinglidazao Xifei Decoction originated from Zhang Zhongjing’s Summary of Synopsis of the Golden Chamber in the Eastern Han Dynasty. It is composed of Descurainia sophia seed and Jujubae fructus. It has the effect of purging the lung and relieving asthma. It is used in the early stage of pulmonary abscess, where wind heat and evil toxins are obstructed in the lungs, resulting in the syndrome of excess evil and qi blockage. It has been respected and used by doctors of all dynasties, and its application scope has been expanded by adding or reducing the flavor of medicine. It is mostly used in modern clinical treatment of lung and heart diseases such as lung cancer, pneumonia, asthma, heart failure, pleural effusion and so on. In this paper, the origin research, formulation and dosage research, chemical composition, modern pharmacology research, modern clinical application and other aspects of Tinglidazao Xifei Decoction were systematically described, which provided theoretical basis for further research and development of this decoction and literature reference for clinical positioning of its preparation.
出处
《临床医学进展》
2024年第6期1327-1336,共10页
Advances in Clinical Medicine
