摘要
目的:报道黏膜相关淋巴组织淋巴瘤(mucosa associated lymphoid tissue, MALT)并干燥综合征(Primary Sjögren’s Syndrome, SS)的临床特点与诊治重点,分析其预后。方法:回顾1例MALT并SS患者的临床资料并复习相关文献。结果:本例报道的MALT并pSS患者以肺部结节为首发表现,无明显伴随症状,经多次肺组织穿刺活检的病理结果不能排除淋巴瘤可能,结合免疫组化结果确诊为MALT合并SS,在疾病进展过程中可根据胸部CT检查结果发现肺内结节的增长趋势,经过治疗后随访,患者现病情稳定。结论:MALT并pSS患者较少,发病隐匿,初期临床表现可不典型,根据临床表现及影像学检查易漏诊,临床医师在疾病诊断过程中需加强对MALT并pSS的认识,及时给予治疗。
Objective: To report the clinical features, diagnosis and treatment of mucosa associated lymphoid tissue (MALT) and Primary Sjögren’s Syndrome (pSS), and analyze its prognosis. Methods: The clinical data of a case of MALT complicated with SS were reviewed and the related literature was reviewed. Results: The patients with MALT and pSS reported in this case presented with pulmonary nodules as the first symptom, and there were no obvious accompanying symptoms. The pathological results of lung biopsy for many times could not rule out the possibility of lymphoma. Combined with immunohistochemical results, MALT with SS was diagnosed. In the process of disease progress, the growth trend of pulmonary nodules could be found according to the results of chest CT examination. After treatment and follow-up, the patient’s condition was stable. Conclusion: There are few patients with MALT complicated with pSS, and the initial clinical manifestations are atypical. According to the clinical manifestations and imaging examination, it is easy to miss the diagnosis. Clinicians should strengthen their understanding of MALT complicated with pSS in the process of disease diagnosis.
出处
《临床医学进展》
2024年第4期2943-2949,共7页
Advances in Clinical Medicine
