摘要
本文就高脂血症的分类、药物治疗的研究进展以及饮食和运动管理方面的重要性进行了综述。首先,高脂血症可分为原发性和继发性两种类型,根据不同的致病因素和遗传背景进行分类。其次,药物治疗方面的研究已取得显著进展,包括降胆固醇药物和降甘油三酯药物等。他汀类药物是降胆固醇治疗的基石,而其他药物如胆固醇吸收抑制剂和PCSK9抑制剂也显示了良好的疗效。此外,降甘油三酯药物如贝特类药物、烟酸类药物和高纯度鱼油制剂在降低甘油三酯水平方面发挥重要作用。最后,饮食和运动管理在高脂血症患者中起着关键作用。通过合理的饮食结构和适度的运动,可以进一步改善血脂水平并降低心血管疾病的风险。
This article provides a comprehensive review on the classification of hyperlipidemia, research pro-gress in drug therapy, and the importance of diet and exercise management. Firstly, hyperlipidemia can be classified into primary and secondary types based on different etiological factors and genetic backgrounds. Secondly, significant progress has been made in drug therapy, including cholester-ol-lowering drugs and triglyceride-lowering drugs. Statins are the cornerstone of cholester-ol-lowering treatment, while other drugs such as cholesterol absorption inhibitors and PCSK9 in-hibitors have also shown good efficacy. In addition, triglyceride-lowering drugs such as fibrates, nia-cin, and high-purity fish oil preparations play an important role in reducing triglyceride levels. Lastly, diet and exercise management play a crucial role in patients with hyperlipidemia. By adopt-ing a balanced diet and engaging in moderate exercise, blood lipid levels can be further improved and the risk of cardiovascular diseases can be reduced.
出处
《临床医学进展》
2024年第1期1635-1646,共12页
Advances in Clinical Medicine
