摘要
目的:本综述的目的是系统评估炎症生物标志物在预测胃癌预后中的作用。通过综合分析现有的研究文献,我们将总结LMR、NLR、PLR和RDW等炎症生物标志物在胃癌预后评估中的预测能力和机制解释。此外,我们还将讨论这些生物标志物在胃癌预后中的临床应用前景和潜在局限性。本综述将按照以下结构展开:首先,我们将回顾胃癌的全球流行病学数据和趋势,以及胃癌的发病率和死亡率。接下来,我们将探讨胃癌的分子亚型和临床表现。然后,我们将详细讨论胃癌预后的重要性和挑战,以及炎症在胃癌发展和预后中的作用。最后,我们将总结炎症生物标志物在预测胃癌预后中的作用,并讨论其临床应用的前景和限制。通过这个综述,我们旨在为胃癌预后评估提供全面的综合视角,为临床实践和进一步研究提供有价值的参考。结论:外周血NLR、PLR、LMR、RDW与胃癌患者预后有一定关系,对胃癌预后具有一定的预测价值。
The aim of the review was to systematically assess the role of inflammatory biomarkers in predicting the prognosis of gastric cancer. By comprehensively analyzing the existing research literature, we will summarize the predictive power and mechanistic explanations of inflammatory biomarkers such as LMR, NLR, PLR, and RDW in the prognostic assessment of gastric cancer. In addition, we will discuss the clinical application prospects and potential limitations of these biomarkers in the prognosis of gastric cancer. This review will be structured as follows: First, we will review the global epidemiological data and trends of gastric cancer, as well as the incidence and mortality of gastric cancer. Next, we will explore the molecular subtypes and clinical manifestations of gastric cancer. Then, we will discuss in detail the importance and challenges of gastric cancer prognosis, as well as the role of inflammation in gastric cancer development and prognosis. Finally, we will review the role of inflammatory biomarkers in predicting the prognosis of gastric cancer and discuss the prospects and limitations of their clinical application. Through this review, we aim to provide a comprehensive perspective for the prognosis evaluation of gastric cancer, and provide a valuable reference for clinical practice and further research. Conclusions: Peripheral blood NLR, PLR, LMR and RDW have a certain relationship with the prognosis of gastric cancer patients, and have certain predictive value for the prognosis of gastric cancer.
出处
《临床医学进展》
2023年第12期19890-19898,共9页
Advances in Clinical Medicine
