摘要
芍药苷(paeoniflorin, PF)主要是从毛茛科植物中提取,是中药白芍和赤芍的主要成分,是一种易溶于水的白色粉末化合物,大量研究表明芍药苷具有保护心脑血管、保护神经细胞、抗炎、抗抑郁、免疫调节等多种作用,目前,芍药苷很少以单体形式应用于临床治疗。本文对国内近五年芍药苷药理作用文献进行查阅,从芍药苷的化学特性、提取与测定、药理作用等方面进行综述,以期为芍药苷的临床和开发提供参考。
Paeoniflorin (PF) is mainly extracted from plants in the Ranunculaceae family and is the main com-ponent of traditional Chinese medicine, Paeonia lactiflora and Paeonia rubra. It is a water-soluble white powder compound. A large number of studies have shown that paeoniflorin has various ef-fects such as protecting cardiovascular and cerebrovascular systems, protecting nerve cells, an-ti-inflammatory, antidepressant, and immune regulation. Currently, paeoniflorin is rarely used as a monomer in clinical treatment. This article reviews literature on the pharmacological effects of paeoniflorin in the past five years in China, including its chemical properties, extraction and deter-mination, pharmacological effects, etc., in order to provide reference for the clinical and develop-ment of paeoniflorin.
出处
《临床医学进展》
2023年第11期17341-17348,共8页
Advances in Clinical Medicine
