摘要
随着生活方式的改变及人口老龄化的加速,2型糖尿病和肥胖的患病率呈快速上升趋势,已成为全球重大公共卫生问题。肥胖是2型糖尿病的重要致病因素,并加速糖尿病慢性并发症的产生。本文就肥胖与糖尿病血管并发症的相关性作一综述,主要包括糖尿病视网膜病变、糖尿病肾病与动脉粥样硬化性心血管疾病,重点关注临床数据、分子机制和治疗前景等方面,以期为糖尿病的早期干预及规范化诊疗提供依据。
With the accelerated lifestyle changes and population aging, the prevalence of type 2 diabetes and obesity is rapidly increasing and has become a global public health problem. Obesity is an im-portant causative factor of type 2 diabetes and accelerates the development of chronic complica-tions of diabetes. In this paper, we review the correlation between obesity and diabetic vascular complications, including diabetic retinopathy, diabetic nephropathy and arteriosclerotic cardio-vascular disease, focusing on clinical data, molecular mechanisms and therapeutic prospects, with the aim of providing a basis for early intervention and standardized diagnosis and treatment of di-abetes.
出处
《临床医学进展》
2023年第3期4686-4693,共8页
Advances in Clinical Medicine
