摘要
目的 :评价血塞通注射液联合长效异乐定治疗冠心病心绞痛的疗效。方法 :6 4例心绞痛患者随机分成两组 ,其中治疗组 33例 ,以血塞通注射液静滴和长效异乐定口服治疗 ;对照组 31例 ,以长效异乐定和肠溶阿司匹林口服治疗。观察用药前后心绞痛症状、硝酸甘油用量和心电图的变化。结果 :治疗组心绞痛症状疗效为显效率 6 6 .6 7% ,总有效率 93.94 % ;硝酸甘油减停率疗效为显效率 75 .76 % ,总有效率 96 .97% ;心电图疗效为显效率12 .12 % ,总有效率 6 6 .6 7%。对照组心绞痛症状疗效为显效率 4 8.39% ,总有效率 80 .6 5 % ;硝酸甘油减停率疗效为显效率 5 8.0 6 % ,总有效率 87.0 9% ;心电图疗效为显效率 6 .4 5 % ,总有效率 5 4 .84 %。治疗组和对照组治疗冠心病心绞痛均有较好的疗效 ,两组间比较无显著性差异。结论 :血塞通注射液治疗冠心病心绞痛疗效显著 。
Objective:The purpose of this study is to evaluate the therapeutic effects of Xuesaitong injectio combined with longacting-sorbidenitrate on angina pectoris. Methods: Sixty-four cases of patients with angina pectoris were randomly divided into two groups. The treatment group(31 cases) was treated with Xuesaitong injectio combined with longacting-sorbidenitrate, and the control group(31 cases) was treated with longacting-sorbidenitrate and aspirin, both of them taken orally. The changes of angina pectoris symptoms, the dosage of sorbidenitrate and ECG were observed before and after treatment. Results: The curative effects of pectoris symptoms in the treatment group was as follows:apparent rate 66.67%, total effective rate 93.94%; effects of decreased dose of sorbidenitrate: apparent rate 75.76%, total effective rate 96.97%; effects of ECG: apparent rate 12.12%, total effective rate 66.67%. In the control group, the symptom effects was as follows: apparent rate 48.39%, total effective rate 80.65%; effects of decreased dose of sorbidenitrate: apparent rate 58.06%, total effective rate 87.09%; effectiveness of ECG: apparent rate 6.45%, total effective rate 54.84%. Well therapeutic effects were reflected from the two groups, and there were no difference between the control and treatment groups and low adverse reactions as well. Conclusion: The therapeutic effect of Xuesaitong injectio in treatment of pectoris is remarkable, which is especially indicated for those pectoris patients who had a contraindication of aspirin.
出处
《山东中医药大学学报》
2004年第3期182-184,共3页
Journal of Shandong University of Traditional Chinese Medicine
