摘要
近年来流行病学和动物实验的观察,发现钙的摄取量与高血压呈反比。随意抽样212例正常妊娠妇女分4组,从妊娠20～28周每天口服钙元素120mg、240mg、lg和2g至分娩,妊高征发生率依次为8.9%、7.1%、8.0%,4%。对照组106例不补钙,妊高征发生率18%。补钙2g组妊高征显著降低,有统计学意义,无副反应。补钙降低妊高征发生率的效果,可能与钙调整血浆甲状旁腺素和肾素活性有关。
The recent epidemiological and animal studies showed an inverse association between calcium intake and incidence of hypertension. A randomized control clinical trial of calcium intake during pregnaney was conducted in 212 pregnant women. The women were divided into 4 groups with 120mg, 240mg, 1g, 2g of calcium element given daily from 20～28 weeks of gestation untill delivery. The incidences of PIH were 8.9%, 7.5%, 8.0% and 4.0% respectively in these groups. The control group of 106 women did not receive calcium gave an incidence of 18%. The supplementation of 2g of calcium daily showed significant effect in lowering the incidence of PIH without any adverse side effect. Mediating plasma parathyroid hormone and renin activity are thought to be the calcium effects on the decreasing the incidence of PIH.
出处
《北京医学》
CAS
北大核心
1992年第5期268-271,共4页
Beijing Medical Journal
