摘要
目的 研究反复自然流产和男性不育症患者染色体的变化。方法 本文采用染色体G显带技术对反复自然流产、男性不育症患者进行染色体核型分析。结果 发现染色体结构异常 2例 ,4 6 ,XX ,t(3;8) (p2 5 ;q13)、4 6 ,XY ,t(1;2 1;14 )(p2 2 ;p11;q13) ,为世界首次报道。结论 研究表明 ,染色体异常是导致反复自然流产、男性不育的重要原因。
Objective: To explore karyotype of patients with male infertilitas or repeated spontaneous abortion. Methods: Abnormal banding technique was used to analyse the karyotype in the objects of male infertilitas or repeated spontaneous abortion. Results: Two cases of abnormal karyotype were detected, which were:46,XY,t(3;8)(p25;q13);46,XY,t(1;21;14)(p22;p11;q13), were never been reported in world. Conclusion: Our results indicated that there is close relationship between chromosomal abnormality and repeated spontaneous abortion or male infertility.
出处
《中国优生与遗传杂志》
2004年第2期43-44,共2页
Chinese Journal of Birth Health & Heredity
关键词
染色体
核型
复杂易位
流产
男性不育
chromosome
karyotype
complex translacation
abortion
male infertilitas
