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Mechanisms for amplified mediator release from colonic mast cells:Implications for intestinal inflammatory diseases

Mechanisms for amplified mediator release from colonic mast cells:Implications for intestinal inflammatory diseases
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摘要 The mast cell is an enigmatic cell type whose physiological function has preoccupied large numbers of investigators for decadest. Some have concluded that the absence of mast cells is incompatible with life, at least in humans, because no human conditions have been documented where these cells are absent from the body. On the other hand, mice harboring specific mutations in certain growth factors, or their receptors, that
作者 Kim E.Barrett
出处 《World Journal of Gastroenterology》 SCIE CAS CSCD 2004年第5期617-619,共3页 世界胃肠病学杂志(英文版)
基金 Supported by the grants from the National Institutes of Health,USA (DK33491 and AT01180) and the Crohn's and Colitis Foundation of America
关键词 COLON Humans Inflammation Mediators Mast Cells Research Support Non-U.S. Gov't Research Support U.S. Gov't P.H.S. 肠道炎症 肥大细胞 炎症介质 免疫球蛋白 分子机制
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