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健胃灵作用机理的实验研究 被引量:5

Experimental Research on the Effective Mechanism of Jianweiling(健胃灵)
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摘要 本实验对健胃灵的作用机理进行了实验研究。结果表明。健胃灵对胃肠运动具有双向调节作用,即当胃肠处于麻痹状态时,该药可明显促其平滑肌峰电活动的恢复;而当胃肠国新斯的明诱发痉孪时,健胃灵则有解痉作用。此外,该药对胰液、胰酶的分泌及小肠吸收功能均有一定促进作用。本实验还将健胃灵的作用与目前疗效肯定的胃动力及止吐药吗丁啉的作用进行了一定的实验对比观察。 The purpose of this study is to find out the effective mechanism of Jianweiling (JWL) in treating some gastrointestinal (GI) diseases. The functions of GI movement, bile and pancreatic secretion and intestinal absorption were measured after giving JWL to the experimental rats. The results showed that JWL could adjust GI movement once it was in abnormal conditions. When the gastrointestine was in paralysis under the influence of abdominal operation, JWL. could make GI myoelectric activity return to normal; and JWL could relax it when the gastrointestine was in a cramp state resulted from Neostigmini Methylsulfurici injection. In addition, the pancreatic secretion, the amylase activity in pancreatic juice and the intestinal absorption for D-xylose in JWL group were obviously better than those of the control groups. These results suggested that the effective mechanism of JWL on some GI diseases can be realized by adjusting and promoting GI functions in various ways.
出处 《中国中西医结合杂志》 CAS CSCD 北大核心 1992年第1期32-34,共3页 Chinese Journal of Integrated Traditional and Western Medicine
关键词 健胃灵 胃肠运动 消化功能 Jianweiling gastrointestinal movement digestive function
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参考文献2

  • 1李永渝,裴德恺,高静涛.腹部手术后早期胃肠功能变化的实验观察[J]贵州医药,1986(04).
  • 2Lionel Bueno DS,Jean-Pierre Ferre BS,Dr. Yves Ruckebusch DVM, DS. Effects of anesthesia and surgical procedures on intestinal myoelectric activity in rats[J] 1978,The American Journal of Digestive Diseases(8):690~695

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