摘要
本文在单眼瞳孔对光反应的实验及模型研究基础上,设计了由计算机控制的双眼交替光刺激方法来进行瞳孔动态反应实验,以了解人的瞳孔控制系统是如何在两眼之间耦合的。实验结果表明在双眼交替光刺激时,虽然两眼所受的光通量总和在任何时刻都是恒定不变的,但是当刺激光在左右眼之间交替瞬时,两眼都同时得出明显的瞳孔动态反应。这就提示了双眼之间耦合必需是在双眼分别受光后产生的控制信号,分别经过正微商的非线性环节后,再进行双眼综合共同控制瞳孔虹膜肌,文中还用状态方程法在PDP11/23计算机上对双眼瞳孔模型进行了仿真,输出波形与实验结果很相近,通过模型仿真,还对临床上应用的“Marcus Gunn Sign”(一种用交替光刺激对单侧视神经炎的检查方法)作出了刺激光最佳交替频率的建议。
<ABSTRACT>
On the basis of monocular pupillary control mechanism, an alterna-
ting light stimuli method was developed for binocular pupillary experi-
ments to investigate the coupling between pupillary systems of two ey-
es in human subject.
Experimental results show: When the two eyes were stimulated
alternately by the light, even the total amount of stimulative light for
two eyes is kept constant, the transient pupil responses in both eyes
were found. These indicated the coupling between two monocular pupi-
llary system is a summation after differentiator and nonliner rectifier.
The binocular model was simulated by statc epuation in PDP11 /23 plus
computer. The model output match the experimental data very well.The
optimal frequency for the clinical Marcus Gunn Sign, a clinical test ut-
ilizing the binocular alternating light stimulation for detecting unilate-
ral afferent defects, was discussed also.
出处
《中国生物医学工程学报》
CAS
CSCD
北大核心
1992年第4期280-289,共10页
Chinese Journal of Biomedical Engineering
基金
国家自然科学基金的部份资助
