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1%盐酸特比奈芬乳膏治疗皮肤癣菌病48例临床疗效观察 被引量:6

Clinical Observation of 1% Terbinafine in Treatment of 48 Patients with Dermatophytosis
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摘要 目的 :探讨 1 %盐酸特比奈芬乳膏外用治疗皮肤癣菌病的临床疗效。方法 :共观察 95例皮肤癣菌病患者 ,其中治疗组 48例 ,外用 1 %盐酸特比奈芬乳膏 ,每日 2次 ;对照组 47例 ,外用 1 %联苯苄唑霜 ,每日 1次 ,两组疗程均 2周 ,比较其临床疗效。结果 :治疗组的临床治愈率、总有效率、真菌清除率稍高于对照组 (P均 >0 0 5 )。结论 :1 %盐酸特比奈芬乳膏外用治疗皮肤癣菌病疗效肯定 ,安全性高 ,可作为临床常规选用外用药之一。 Objective:To explore the effcacy of the 1% terbinafine hydzochloride cream in treatment of dermatophylosis. Methods:95 cases with dermatophytosis were devided into 2 groups. The study group (n=48) were treated with 1% terbinafine hydzochloride cream for topical use on skin lesions twice per day for 2 weeks, control group (n=47) were treated by 1% bifonazole creams for topical use daily for 2 weeks. Results:The cured rate, total effective rate fungi clearance rate were showed a litter bit higher than that in control (P>0.05). Conclusion:1% terbinafine hydzochloride is a good and safe medication in treatment of dermatophytosis.
出处 《岭南皮肤性病科杂志》 2004年第1期31-32,43,共3页 Southern China Journal of Dermato-Venereology
关键词 1%盐酸特比奈芬乳膏 药物治疗 皮肤癣菌病 外用药 1%联苯苄唑霜 1%Terbinafine hydzochloride cream Dermatophytosis Treatment efficacy
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  • 1[2]Sanchez Carazo JL, Fuente C, Oliver V, et al. Estudio comparative de terbinnafina vs. bifonazol crema al 1% en application unica diariaen tina pedis [J]. Actas Dermo Sifliogr,1994, 86(5) :388 - 394.
  • 2王爱平,李若瑜,曾凡钦,赖维,万哲,朱学骏.1%盐酸特比萘芬软膏治疗浅部真菌病随机双盲对照多中心临床试验[J].临床皮肤科杂志,2001,30(4):247-249. 被引量:25
  • 3[4]Faergemann J, Zehemer H, Boukhabza A, et al. Comparision of trebinafine levels in stratum and dermis - epidermis (without strayum corneum) after topical combine with oral therapy in healthy volunteers[J]. J Eur Acad Dermatol Venerol, 1995, 5 (suppl 1):94.

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