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围手术期肺炎危险因素病例对照研究 被引量:18

A case-control study on risk factors in perioperative nosocomial pneumonia
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摘要 目的 探讨引起围手术期院内感染性肺炎 (Nosocomialpneumonia ,NP)的最危险因素 ,制成Logistic数学模型 ,预测NP的发生。方法 NP患者及对照组各 65例 ,采用病例 -对照设计方案对引起NP的危险因素 ,以单因素、多因素等方法进行统计分析。结果 单因素分析 65例NP危险因素 ,其中麻醉方式、意识、置鼻胃管、手术时间、气管切开等因素OR值 (危险度 )、χ2 和 95%CI(可信度 )均有显著意义 ;多因素分析置胃管是一独立的危险因素 ,在不存在昏迷、吸烟等因素情况下仍可发挥作用 ;量效关系 :置胃管、手术时间越长NP发生率越高。结论 麻醉方式、意识、吸烟史、置胃管、手术时间、气管插管和切开等是引起NP的危险因素 ;Logistic数学模型预测NP有一定的应用价值 。 Objective To find the risk factors of periopertive nosocomi a l pneumonia(NP) and develop a logistic mathematic model to forecast the occurenc e of NP.Methods Two groups of patients with perioperative NP a nd matched controls,65 each,were investigated,and a case control study was des igned to analyse the risk factors of NP.Single factor and multi factor statisti cal analyses were used.Results Single factor analysis of 65 cas es s howed that mode of anaesthesia,consciousness,intubation of nasogastric tube,dura tion of operation,and tracheotomy were of significance in odds ratio,chi square test,and 95% confidence interval.The intubation of nasogastric tube was a indep endent risk factor by multi factor analysis,still having effect without such fa ctors as unconsciousness and smoking.The longer the duration of nasogastric tube indwelling and surgical operation,the higher the incidence of NP.Conclu sions The risk factors of NP are mode of anaesthesia,unconsciousness,s moking,intubation of nasogastric tube,duration of surgical operation,and tracheo tomy.The logistic mathematic model is of use value in forecasting NP in the risk patients,thereby facilitating prevention and reduction of NP.
出处 《武警医学》 CAS 2004年第1期25-28,共4页 Medical Journal of the Chinese People's Armed Police Force
关键词 围手术期 肺炎 危险因素 病例对照研究 Nosocomial pneumonia Risk factor Multi factor anal ysis
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参考文献3

  • 1Josh N, Brown S, Borg P et al. A predictive risk index for nosocomial pneumonia in the intensive cam unit.Am J Med, 1992,93:135 - 142.
  • 2Fick RB. Lung humoral response to pseudomonas species. Eur J Clin Microbiol Infect Dis, 1989,8.29 - 34.
  • 3Moossa AR, Mayer D, Lavell - Jones M. Surgical complications. In: Sabinston DC Jr ed. Textbook of surgery. 15 th ed, philadelphia: Saundersy, 1997. 299 - 315.

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