摘要
目的 :探讨罗哌卡因联合地塞米松进行踝周神经阻滞麻醉对拇外翻患者术后镇痛效果的影响。方法 :选取我院2016年6月-2017年2月在踝周神经阻滞麻醉下行手术治疗的拇外翻患者40例,美国麻醉师协会(ASA)分级标准Ⅰ级或Ⅱ级,按随机数字表法分为安慰剂组(组Ⅰ)及地塞米松组(组Ⅱ),各20例。采用麻醉药物:组Ⅰ0.5%罗哌卡因20 m L+0.9%氯化钠注射液1 m L;组Ⅱ0.5%罗哌卡因20 m L+5 mg地塞米松1 m L。麻醉完成30 min后开始手术。术后记录以下数据:患者首次疼痛时间以及术后6,9,12,15,18 h患者的视觉模拟评分(VAS)。结果:组Ⅱ较组Ⅰ首次疼痛时间明显延长(P<0.05),组Ⅱ术后6,9,12 h疼痛程度均明显低于组Ⅰ(P<0.05)。结论 :罗哌卡因联合地塞米松进行踝周神经阻滞麻醉可明显减轻拇外翻患者术后的疼痛程度,并延长术后镇痛时间。
Objective:To investigate the effect of ropivacaine combined with dexamethasone on postoperative analgesia in patients undergoing hallux valgus surgery under block anesthesia of peripheral nerves of ankles. Methods:40 patients with hallux valgus undergoing hallux valgus surgery under block anesthesia of peripheral nerves of ankles in our hospital from June 2016 to February 2017, ASA Ⅰ or Ⅱ, were selected and randomly divided into placebo group(group Ⅰ, n=20) and dexamethasone group(group Ⅱ, n=20). The patients in the group Ⅰ were treated with 0.5% ropivacaine 20 ml plus 0.9% Na Cl injection 1 ml. The patients in the group Ⅱwere treated with 0.5% ropivacaine 20 ml plus 5 mg dexamethasone 1 ml. The operation was started after 30 min of anesthesia. The following data: patient's first pain time and visual analogue scale(VAS) at 6, 9, 12, 15, 18 h after operation were recorded. Results:The first pain time in the group Ⅱ was significantly prolonged compared with that in the group Ⅰ(P<0.05), and pain degree at 6, 9, 12 h after operation in the group Ⅱ was significantly lower than that in the group Ⅰ(P<0.05). Conclusions:The combined use of ropivacaine combined with dexamethasone for block anesthesia of peripheral nerves of ankles can significantly reduce postoperative pain degree of patients with hallux valgus and prolong postoperative analgesia time.
出处
《中国执业药师》
CAS
2018年第4期26-29,共4页
China Licensed Pharmacist