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黄连素配合十灰散治疗宫颈柱状上皮异位的疗效及安全性研究

The Study of Curative Effect and Safety of Berberine Combined with Shihui Powder in Patients with Cervical Ectopic Columnar Epithelium
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摘要 目的 :探讨黄连素配合十灰散治疗宫颈柱状上皮异位的临床效果及安全性。方法 :选择2016年4月-2017年3月我院收治的宫颈柱状上皮异位患者90例,按随机数字表法分为对照组和观察组,各45例。对照组采用物理微波治疗,观察组采用黄连素配合十灰散(粉剂隔天一次,洗剂每天一次)治疗,比较两组临床疗效及安全性。结果 :观察组治疗后尿路刺激征时间、腹部胀痛消失时间、阴道排液及创面愈合时间,均短于对照组(P<0.05);观察组治疗后不良反应发生率为8.89%,与对照组13.33%比较,差异无统计学意义(P>0.05)。结论 :黄连素配合十灰散治疗宫颈柱状上皮异位效果理想,安全性高,值得推广应用。 Objective:To evaluate the clinical effect and safety of berberine combined with shihui powder in patients with cervical ectopic columnar epithelium.Methods:90 cases of epithelial heterotopic epithelium were treated in our hospital between April 2016 and March 2017 who were randomly divided into control group(n=45) and observation group(n=45).The control group was treated with the physical microwave therapy,while the observation group was treated with berberine combined with shihui powder(the power was given every other day,while the lotion was given once a day).The clinical efficacy and safety of the two groups were compared.Results:After treatment,the duration of the urinary stimulation,the duration of the abdominal distended pain,the vaginal discharge as well as the wound healing time in the observation group were shorter than those in the control group(P<0.05).But there was no significant defference between the observation group(8.89%) and the control group(20.59%) in adverse reactions(P>0.05).Conclusion:Berberine with shihui powder presents effective effects in patients with cervical ectopic columnar epithelium with reasonable safety,providing broad prospects in clinic application.
作者 孙丹
出处 《中国执业药师》 CAS 2017年第12期16-18,共3页 China Licensed Pharmacist
关键词 黄连素 十灰散 宫颈柱状上皮异位 临床效果 安全性 Berberine Shihui Powder The Cervical Columnar Epithelium Clinical Effect Security
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