摘要
原发性恶性间皮瘤少见,国外尸检病例仅占0.01～0.1％。我院2,358例尸检中有6例(心包、腹膜、胸膜各2例),占尸检数的0.25％。在临床和病理学上,对本病的诊断均较困难。本文结合文献着重探讨其诊断等问题。
Six cases of malignant mesothelioma by autopsy confirmation are reported. They can be divided into five histologic types: tubulopapillary, fibrosarcomaoid, undifferentiated, mesothelial cell and mixed cell types. These data suggest that diagnosis of the malignant mesothelioma may be ascribed to (1) tumor strictly localized to body cavity viscera lamina or parietal lamina, but no other primary tumor, (2) often two or more types were present in one tumor, (3) no basement membrane between epithelial cells and stroma, (4) hyperplasia mesothelial cells and malignant areas may coexist with definite areas of dysplastic transition, (5) malignant mesothelioma cells contained a large amount of hyaluronic acid, strong positive for Alcian blue stains. In addition, we also discussed the pathogenesis of the malignant mesothelioma.
出处
《肿瘤防治研究》
CAS
1987年第4期199-202,258,共5页
Cancer Research on Prevention and Treatment
