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小鼠移植性肿瘤生长的性别差异及其原因探讨 (I)小鼠移植性肿瘤生长及其对刺激(瘤内注射生理盐水)和免疫治疗(瘤内注射活卡介苗和/或肌肉注射胸腺素)反应的性别差异

Study of Sex Differences in Growth of Implanted Tumors in Mice and of Their Causative Factors. I. Sex Differences of the GrowthFollowing Intralesional Injection of Physiological Saline_i BCG and/or Thymosin
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摘要 临床上男性恶性肿瘤的发病率显著高于女性,肿瘤实验中也早已观察到这种性别差异。本文报告小鼠移植性实体型肉瘤180的生长在雄性小鼠比雌性快,而且小鼠移植性实体型肉瘤180和肝癌对于局部刺激(瘤内注射生理盐水)和免疫治疗(瘤内注射活卡介苗和/或肌肉注射胸腺素)的反应也有性别差异。 Human cancer incidence in male is higher than in females. Similar differences exist in animals and in animals in contact with various carcinogens. The growth rate of subcutaneously implanted sarcoma 180, in the present experiments, is faster in males than in the females. Similar growth differeences are found in subcutaneously implanted sarcoma 180 and hepatoma with intralesional injection of physiological sa line, BCG, and/or intramuscular injection of thymosin.
出处 《中国肿瘤临床》 CAS 1981年第2期120-122,共3页 Chinese Journal of Clinical Oncology
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