摘要
目的:探讨金天格胶囊对原发Ⅰ型骨质疏松症患者下肢功能的影响。方法:采用临床随机对照的方法,将160例符合纳入标准的原发Ⅰ型骨质疏松患者随机分为对照组和治疗组:治疗组给予金天格胶囊;对照组给予钙尔奇D片。疗程为12周。治疗前后分别比较患者的SPPB(简易机体功能评估量表),TUG(计时起走测试),BMD(骨密度),RASM(四肢骨骼肌指数)以及股四头肌力,SPPB包括5次坐立测试、串联站立测试和2.44 m行走测试。结果:除RASM外,治疗组的各项研究指标均优于治疗前,差异有统计学意义(P<0.05);对照组则同治疗前差异无统计学意义(P>0.05)。结论:金天格胶囊能够有效地改善和增强原发I型骨质疏松患者的下肢功能,减少患者发生跌倒事件的概率,从而起到有效预防骨质疏松性骨折的效果。
Objective:To investigate the effect of Jintiange capsules on lower limb function in patients with primary type I osteoporosis.Methods:160 patients with primary type I osteoporosis who met the inclusion criteria were randomly divided into control group and treatment group by clinical randomized control method.The treatment group was given Jintiange capsules and the control group was given calcium carbonate and vitamin D3 tablets.The course of treatment was 12 weeks.The SPPB(short physical performance battery),TUG(timed up and go test),BMD(bone density),RASM(skeletal muscle index of limbs)and quadriceps muscle strength of the patients were compared before and after treatment,and the SPPB included five sitting test,tandem standing test and 2.44 m walking test.Results:Except for RASM,all the research indexes in the treatment group were better than before,and the difference was statistically significant(P<0.05).There was no significant difference between the control group and the group before treatment(P>0.05).Conclusion:Jintiange capsules can effectively improve and enhance the lower limb function of patients with primary type I osteoporosis,reduce the probability of falling events in patients,and thus effectively prevent osteoporotic fractures.
作者
袁一峰
黄小生
杨依然
刘康
史晓林
YUAN Yifeng;HUANG Xiaosheng;YANG Yiran;LIU Kang;SHI Xiaolin(The Second Clinical Medical College of Zhejiang Chinese Traditional Medical University,Hangzhou310053,China;The Second Affiliated Hospital of Zhejiang Chinese Traditional Medical University,Hangzhou310005,Chin)
出处
《中国中医骨伤科杂志》
CAS
2019年第8期24-27,31,共5页
Chinese Journal of Traditional Medical Traumatology & Orthopedics
作者简介
通信作者:史晓林,E-mail:xlshi-2002@163.com
