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胰腺神经内分泌肿瘤肝转移分子机制研究进展 被引量:1

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摘要 胰腺神经内分泌肿瘤(pancreatic neuroendocrine neoplasms,pNENs)是一类相对罕见的胰岛细胞起源的肿瘤,占所有胰腺肿瘤的1%~2%。pNENs的组织学特征、生物学行为及临床表现具有高度异质性。2018年世界卫生组织(WHO)专家共识建议将pNENs归类为分化好的神经内分泌'瘤'(neuroendocrine tumor,NET)和分化差的神经内分泌'癌'(neuroendocrine carcinoma,NEC),前者根据肿瘤增殖活性(核分裂像及Ki-67)再划分为高(G1)、中(G2)、低(G3)级别NET,后者则依据细胞形态划分为小细胞型和大细胞型NEC[1]。
出处 《中国实用外科杂志》 CSCD 北大核心 2019年第9期976-978,共3页 Chinese Journal of Practical Surgery
关键词 胰腺神经内分泌肿瘤 肝转移 分子机制 pancreatic neuroendocrine neoplasm liver metastases molecular mechanism
作者简介 通信作者:楼文晖,E-mail:lou.wenhui@zs-hospital.sh.cn
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  • 10楼文晖.转移性胰腺神经内分泌肿瘤综合治疗[J].中国实用外科杂志,2010,30(9):745-748. 被引量:4

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