摘要
目的 评价复方可待因 (可待因∶阿斯匹林 =1∶2 5)的镇痛作用。方法 镇痛作用采用小鼠热板法 ,醋酸扭体法和大鼠甩尾法。结果 复方可待因 (剂量为可待因 1 4mg/kg、阿斯匹林 352mg/kg)可以抑制小鼠由热板和醋酸以及大鼠由光辐射引起的痛反应。结论 复方可待因具有较好的镇痛作用 。
Objective To evaluate analgesic effect of com po und codeine (codeine∶aspirin=1∶25) Methods Analgesic effect w as determined by hot-plate and acetate acid in mice and tail-flicking in rats Results Compound codeine (codeine 14 mg/kg and asprin 352 mg /kg) inhibited the pain reaction induced by hot-plate and acetate acid in mice and pain reaction induced by light radiation in rats Conclusion Analgesic effect of compound codeine is better than that of its components
出处
《安徽医科大学学报》
CAS
2003年第2期122-124,共3页
Acta Universitatis Medicinalis Anhui