摘要
目的:研究伤寒甲型副伤寒结合疫苗在在动物身上产生的抗体抵挡伤寒和甲型副伤寒沙门菌的攻击情况。方法:用分别含2.5μg伤寒V i多糖和甲型副伤寒O多糖、伤寒甲型副伤寒结合疫苗免疫小鼠,免疫结束后9~11天分别用伤寒沙门菌和甲型副伤寒沙门菌进行攻击,观察小鼠存活情况,同时跟同剂量伤寒V i多糖和甲型副伤寒O多糖组进行比较。结果:伤寒甲型副伤寒结合疫苗在抵挡毒菌攻击方面比单纯的伤寒V i多糖/甲型副伤寒O多糖组表现了更好的保护力。结论:我公司研制的伤寒甲型副伤寒结合疫苗在小鼠身上产生的抗体在抵挡毒菌攻击方面表现了很好的保护力。
Objective Research about the antibody of Royal company developed typhoid and paratyphoid A conjugate vaccine produced in animals is to resist the attack of typhoid and paratyphoid fever cases Salmonella.Methods Typhoid and paratyphoid A conjugate vaccine containing respectively 2.5μg typhoid Vi polysaccharide and paratyphoid A polysaccharide immunized mice,9 to 11 days after immunization with typhoid Salmonella and S.paratyphi attack,mice were observed for survival,but with the same dose of typhoid Vi polysaccharide and paratyphoid A polysaccharide O groups were compared.Research about Protection Of Typhoid and paratyphoid A conjugate vaccine.Results Typhoid and paratyphoid A conjugate vaccine germs to resist attacks than mere Vi polysaccharide typhoid/paratyphoid A polysaccharide O group showed better protection force.Conclusions The typhoid and paratyphoid A conjugate vaccine in the binding of the antibody produced in mice to resist germs attacks demonstrated better protection force.
出处
《影像研究与医学应用》
2017年第18期158-159,共2页
Journal of Imaging Research and Medical Applications
