摘要
目的探讨乳腺癌保乳手术治疗后同侧乳腺复发的临床病理特点以及预后情况。方法对我院2010年1月至2013年1月接诊50例乳腺癌保乳手术治疗后同侧乳腺复发患者的临床病历资料进行回顾分析。对比分析其临床病理特点,统计五年总生存率及五年无病生存率。结果异象限复发患者ER状态变化率及PR状态变化率明显高于同象限复发组。初诊p N分期N0-N1、初诊Luminal型、复发肿瘤最大直径<3cm、复发后手术治疗患者的五年总生存率明显较高,初诊p N分期N0-N1、复发后手术治疗患者的五年无病生存率较高。不同手术治疗方案对生存率无明显影响。结论乳腺癌保乳手术后同侧乳腺复发以同象限为主,不同象限复发患者存在明显病理特点差异性。患者初诊病理特点影响患者复发后的生存情况。复发后手术治疗可提升患者五年生存率,不同手术方案对于预后生存率无影响。
Objective To investigate the clinicopathological features and prognosis of ipsilateral breast recurrence after breast conserving surgery. Methods The clinical medical records of 50 patients with breast recurrence after breast conserving surgery from January 2010 to January 2013 were retrospectively analyzed. The clinical and pathological features were compared and analyzed,and the five-year overall survival rate and five-year disease-free survival rate were calculated. Results The rate of change of ER status and the rate of change of PR status in patients with recurrent quadrants were significantly higher than those in the same quadrant recurrence group( P<0. 05). The five-year overall survival rate of newly diagnosed pN stage N0-N1,newly diagnosed Luminal type,recurrent tumor diameter<3 cm,and postoperative recurrence was significantly higher. The five-year disease-free survival rate of patients with newly diagnosed pN stage N0-N1 and postoperative recurrence was higher. Different surgical treatment options had no significant effect on survival rate. Conclusion The breast cancer recurrence after breast-conserving surgery is mainly in the same quadrant. Patients with different quadrant recurrence have obvious pathological characteristics. The pathological characteristics of the patient’s initial diagnosis affect the survival of the patient after recurrence. Surgical treatment after recurrence can improve the five-year survival rate of patients,and different surgical procedures have no effect on the prognosis survival rate.
作者
任殿泉
乌仁高娃
REN Dianquan;WU Rengaowa(Department of Breast Surgery,Inner Mongolia Baotou Cancer Hospital,Inner Mongolia Baotou 014030;Inner Mongolia Baotou Qingshan District Unity Street Maternal and Child Health Center,Inner Mongolia Baotou 014030,China)
关键词
乳腺癌
保乳手术
复发
病理
预后
breast cancer
breast-conserving surgery
recurrence
pathology
prognosis
作者简介
通信作者:乌仁高娃,邮箱:36029097@qq.com。
