摘要
目的对75岁及以上的男性病人资料进行分析,比较不同类型冠心病的血脂代谢情况,观察其中差别的临床意义。方法82例≥75岁的住院男性冠心病病人,分稳定型心绞痛(SA,35例)、不稳定型心绞痛(UA,30例)和急性心肌梗死(AMI,17例)三组,比较各组病人的基础资料,TC、TG、LDL-C、HDL-C、ApoA1、ApoB100、LP(a)的浓度,以及TC/HDL-C、LDL-C/HDL-C和ApoB100/ApoA1。进一步将UA和AMI病例合并再与SA组比较。结果三组病人基础资料无明显差别(P>0.05)。AMI和UA两组的TC、LDL-C、ApoB100浓度及TC/HDL-C、LDL-C/HDL-C、ApoB100/ApoA1比例均高于SA组,而HDL-C浓度均低于SA组,进一步将AMI和UA病人合并再与SA组比较,结果相同(P<0.05)。结论通过对75岁及以上老年男性冠心病患者的血脂代谢进行分组分析,我们发现血清TC、LDL-C和HDL-C浓度及TC(LDL-C)/HDL-C,在老年冠心病的发展过程中预测急性冠脉事件有重要意义,而ApoB100和ApoA1浓度及其比值亦具有一定的价值。
Objective The blood lipid metabolism in elderly male patients with different types of coronary heart disease(CHD)was studied to evaluate the clinical significance of the difference amon g them.Methods 82male in -patients with CHD were divided into three groups:s table angina(SA),35cases;unstable angina(UA),30cases and acute myocardial infarction(AMI ),17cases.Basic characteristics of every patient were studied.We measu red the concentrations of serum TC,TG,HDL -C,LDL -C,ApoA 1 ,ApoB 100 and LP(a),then calculated the ratios of TC /HDL -C,LDL -C /HDL -C and ApoB 100 /ApoA 1 .Results The base·line characteristics of three group s were similar.The concentrations o f TC,LDL -C,ApoB 100 and the ratios of TC /HDL -C,LDL -C /HDL -C,ApoB 100 /ApoA 1 of both group AMI and group UA were hig her than those of group SA(P<0.05),while the levels of HDL -C in the form er two groups were lower than that of group SA(P<0.05).Furthermore,when the protocols of group UA were combined with those of g roup AMI and compared with those of group SA,we gained the similar resul ts(P<0.05).Conclusions Our study suggested that TC,LDL -C,HDL -C and the ratios of TC(LDL -C)/HDL -C played an important role in th e development of the coronary heart disease in elderly males,especially in the acute coronary events.[
出处
《老年医学与保健》
CAS
2003年第3期155-157,共3页
Geriatrics & Health Care
