摘要
目的分析蕈样肉芽肿的诊断治疗现状,加强对蕈样肉芽肿的认识,提高对蕈样肉芽肿的诊断和治疗水平。方法回顾性分析6例蕈样肉芽肿患者的临床诊疗情况,并进行随访,结合相关文献复习。结果 6例患者临床表现多样且不具有特异性,早期诊断皆不明确,确诊均有赖于组织病理结果。1例ⅡA期患者行全身电子线照射,随访2年至今无复发。5例ⅡB期患者中1例行BACOP方案联合化疗、2例行全身电子线照射(TSEI)、2例行TSEI联合CHOP方案化疗,其中1例控制不佳随访8个月后死亡;另外3例随访至今无复发。结论蕈样肉芽肿病变部位多样化,临床表现复杂且不具特异性,早期诊断困难,需综合分析患者病史与各项辅检结果,排除其它疾病作出诊断,组织病理学结果是关键性诊断依据。根据临床分期选择不同的治疗方式可达较好治疗效果。
Objective To analyze the current diagnostic situation of mycosis fungoides ( MF) ,enhance the understanding of MF and improve the diagnosis and treatment level .Methods Clinical data of 6 cases of MF were retrospectively analyzed ,fol-low-up was conducted and literature review was studied .Results The clinical manifestations were different and not specific in the 6 cases.The primary diagnosis were not clear and the final diagnosis depended on histopathologic examination .1 stageⅡA pa-tient underwent TSEI ,and there was no recurrence during 2-year follow-up.In the 5 stageⅡB patients,1 was treated with BACOP combined chemotherapy ,2 with TSEI and 2 with CHOP combined TSEI .3 cases achieved remission ,and 1 progressed and dead in 8 months.Conclusion MF has complicate clinical manifestations and non-specific features .The early diagnosis is difficult .It needs to analyze the patients ’ history and all assistant examination results ,as well as exclude other disease to get the right diagno-sis.Histopathologic result is important for definite diagnosis .An optimal curative effect can be achieved through a suitable thera-peutic option that is based on histopathology and clinical staging .
出处
《实用癌症杂志》
2014年第8期1013-1014,1017,共3页
The Practical Journal of Cancer
关键词
蕈样肉芽肿
组织病理学
诊断
治疗
Mycosis fungoides
Histopathology
Diagnosis
Treatment
