摘要
目的观察原因不明复发性流产(URSA)患者中西医结合治疗前后免疫功能的变化。方法将102例患者随机分成两组。治疗组52例,给予寿胎丸口服,同时肌注黄体酮,绒毛膜促性腺激素(HCG),对照组50例,仅肌注黄体酮及HCG。采用酶联免疫方法测试两组治疗前后患者血液中白介素-2(IL-2)、γ干扰素(IFN-γ)、白介素-10(IL-10)、转化生长因子-β(TGF-β)的浓度,并进行比较。结果治疗后,两组总有效率比较,差异有统计学意义(P<0.05)。治疗后两组IL-2、IFN-γ、IL-10、TGF-β浓度与治疗前比较,差异均有统计学意义(P<0.05)。治疗后组间比较,差异有统计学意义(P<0.05)。结论中药配合激素疗法从"健脾补肾论治"有效治疗URSA,可能是通过增强母胎免疫保护而安胎。
Objective To observe the changes in the immune function in the patients of unknown recurrent spontaneous abortion( URSA) before and after treatment with integrated Chinese and western medicine. Methods One hundred and two patients were randomized into two groups. In the treatment group,52 cases were treated with oral administration of shoutaiwan and muscular injection with progesterone and HCG.In the control group,50 cases were treated with only muscular injection of progesterone and HCG. ELISA method was used to determine the concentrations of IL- 2,IFN- γ,IL- 10 and TGF- β. The comparison was made. Results The difference in the total effective rate was significant between the two groups( P <0. 05). The differences in the concentrations of IL- 2,IFN- γ,IL- 10 and TGF- β were significant before and after treatment in the two groups( P < 0. 05). The differences were significant after treatment in comparison of the two groups( P < 0. 05). Conclusion The combined therapy of Chinese herbal medicine and hormone treatment achieves the effective result for URSA in terms of strengthening the spleen and tonifying the kidney,which is possibly via strengthening the immune function of the pregnant women for fetus protection.
出处
《世界中西医结合杂志》
2016年第7期990-992,共3页
World Journal of Integrated Traditional and Western Medicine
关键词
中西医结合
原因不明复发性流产(URSA)
TH细胞
Integration of Chinese and Western Medicine
Unknown Recurrent Spontaneous Abortion
Th Cells
