摘要
在我国、南亚及东南亚地区,蜂蛰伤事件时常发生,已经成为一个严重威胁广大民众生命和健康的问题。蜂蛰伤导致的急性肾损伤(AKI)是非常常见的严重并发症,病情凶险,危及患者生命。急性肾小管坏死(ATN)是其主要肾脏病理改变。目前认为低血压引起的缺血性肾损伤、血管内溶血、横纹肌溶解和蜂毒直接毒性作用是蜂蛰伤致AKI的主要机制。血液净化治疗是目前救治蜂蛰伤后AKI的有效方法,同时蜂毒的免疫治疗主要针对蜂毒过敏人群。本文就蜂蛰伤导致的AKI防治研究的最新进展作一综述。
In China,South Asia,and Southeast Asia,bee stings often occur and have become a serious threat to the lives and health of the vast numbers of civilians.Acute kidney injury(AKI)caused by bee stings is a very common serious complication,and the condition is dangerous and can endanger the life of the patient,with acute tubular necrosis(ATN)being the major renal pathological change.It is currently believed that the main mechanisms of AKI caused by bee stings includes hypotension-induced ischemic renal injury,intravascular hemolysis,rhabdomyolysis,and direct renal toxicity of bee venom components.Blood purification therapy is an effective method to treat AKI caused by bee stings,and the venom-specific immunotherapy is mainly aimed at the allergic population.This paper reviewed the recent advances in the research on prevention and treatment of AKI caused by bee stings.
作者
张彬
何娅妮
Zhang Bin;He Yani(Nephrology Department,Army Specialty Medical Center,Chongqing 400042,China)
出处
《中华肾病研究电子杂志》
2019年第1期38-40,共3页
Chinese Journal of Kidney Disease Investigation（Electronic Edition）
关键词
蜂蛰伤
急性肾损伤
血液净化
免疫治疗
Bee stings
Acute kidney injury
Blood purification
Immunotherapy
作者简介
通信作者:何娅妮,Email:heynmail@yahoo.com
