摘要
目的研究2013至2017年北京市通州区妊娠期高血压疾病(HDP)的流行情况及其影响因素,为疾病预防和控制提供理论依据。方法基于北京市通州区妇幼保健院的电子信息系统,构建北京市通州区妇幼保健院2013年1月至2017年12月期间分娩的单胎孕妇的回顾性队列,并采用泊松回归模型分析不同危险因素对HDP发病的影响。结果 2013年至2017年期间北京市通州区妇幼保健院的HDP患病率为5.48%,且呈逐年增长趋势,其中子痫前期-子痫最高(2.86%),慢性高血压并发子痫前期最低(0.21%)。受孕时季节因素、母亲受教育程度、高龄情况、孕前体重和产次情况均为妊娠期高血压和子痫前期-子痫的影响因素(χ~2值分别为7.127、24.375、16.221、410.227、46.455,均P<0.05)。以夏季作为参照,春季受孕为发病的危险因素,RR=1.274,P<0.05;以母亲受教育程度为大学及以上作为参照,专科类院校、高中及以下均为危险因素,RR值分别为1.279、1.366,均P<0.05;以非高龄母亲作为参照,高龄母亲为危险因素,RR=1.539,P<0.05;以孕前正常体重作为参照,孕前消瘦为保护性因素,而孕前超重、肥胖均为危险因素,RR值分别为0.580、2.094、3.376,均P<0.05;以经产妇作为参照,初产妇是危险因素,RR=1.936,P<0.05。结论北京市通州区在2013至2017年期间HDP的患病率呈逐年增长趋势,其中子痫前期-子痫最高。受孕时季节、受教育程度、年龄、孕前体重和产次是HDP的影响因素,在HDP的预防和控制工作中应予以重视。
Objective To analyze the prevalence and influencing factors of hypertension disorders in pregnancy(HDP)in Tongzhou District during 2013 to 2017,so as to provide theoretical basis for prevention and control for HDP.Methods A retrospective cohort including pregnant women who underwent singleton deliveries in Tongzhou Maternal&Child Health Hospital of Beijing from January 2013 to December 2017 was set up based on electronic information system of the hospital.We analyzed the influence of different risk factors on HDP by using Poisson regression model.Results From 2013 to 2017,the prevalence of HDP was 5.48%with an increasing trend.The prevalence of preeclampsia-eclampsia was highest(2.86%)and that of chronic hypertension complicating preeclampsia was lowest(0.21%).Conceiving season,educational level,advanced maternal age,pregestational weight and parity were influencing factors of HDP and preeclampsia-eclampsia(χ~2 value was 7.127,24.375,16.221,410.227 and 46.455,respectively,all P<0.05).When compared with the women conceived in summer,women conceived in spring had higher risk of HDP(risk ratio(RR)=1.274,P<0.05)Women with lower education levels of college and senior middle school had higher risk of HDP when compared with those with higher education levels(RR value was 1.279 and 1.366,respectively,both P<0.05).When compared with the women in non-advanced age,advanced age was a risk factor(RR=1.539,P<0.05).Prepregnant thin shape was a protective factor,while prepregnant overweight and obesity were risk factors(RR value was 0.580,2.094 and 3.376,respectively,all P<0.05).Primipara was a risk of HDP(RR=1.936,P<0.05).Conclusion With an increasing prevalence of HDP during 2013 to 2017 in Tongzhou District in Beijing,the prevalence of preeclampsia-eclampsia is highest.We should pay attention to the following factors including conceiving season,educational level,age,pregestational weight and parity in the prevention and control of HDP.
作者
杨洁
林力孜
刘峥
金楚瑶
王海俊
YANG Jie;LIN Lizi;LIU Zheng;JIN Chuyao;WANG Haijun(Tongzhou Maternal&Child Health Hospital of Beijing,Beijing 101100,China;Department of Maternal and Child Health,School of Public Health,Peking University,Beijing 100191,China)
出处
《中国妇幼健康研究》
2019年第4期433-437,共5页
Chinese Journal of Woman and Child Health Research
基金
北京市自然科学基金资助项目(7162106)
北京市通州区科技计划资助项目(KJ2018CX000)
关键词
妊娠期高血压疾病
子痫前期
流行情况
影响因素
hypertension disorders in pregnancy(HDP)
preeclampsia
prevalence
influencing factor
作者简介
第一作者:杨洁(1982—),女,回族,统计师,硕士,主要从事妇幼保健与信息管理、医疗数据分析的研究;第一作者:林力孜(1990—),男,在读博士研究生,主要从事妇幼健康的研究;通讯作者:王海俊,教授。
