摘要
目的 评价思密达治疗婴幼儿诺瓦克样病毒 (NL V)腹泻的效果。方法 选择我院门诊及住院的年龄在 1月～ 3岁的婴幼儿腹泻患者共 177例 ,RT- PCR检测 NL V阳性者随机给予口服思密达加病毒唑或病毒唑 (对照 )治疗。结果 NL V感染阳性 6 3例 ,阳性率 35 .5 9%。思密达加病毒唑治疗组 6 d治愈率为 93.5 5 % (2 9/ 31) ,高于对照组 (75 .0 1% 2 4 / 32 ,P=0 .0 38)。治疗组的平均恢复时间为 3.1d± 1.2 6 d,对照组为 5 .2 d± 0 .93d,t=6 .0 6 ,P=0 .0 11)。
Objective To study on evaluation of the smecta in infants with diarrhea for Norwalk like virus(NLV)in infection.Methods 177 patients at the age of 1 month to 3 years old with non bacterial diarrhea were choosed,who were seen at the Pediatric Outpatient Department and admitted into the Pediatric Ward,Fujian Provincial Hospital.Reverse transcription polymerase chain reaction(RT PCR)was used to detect NLV from stool specimens collected from patients.Smecta plus/or Ribavirin tablet were used in NLV infection positive by RCT(random contrast test).Results Out of 177 stool specimens,35 59%(63/177)were NLV positive detected by RT PCR,which divided tratment group and contrast group.In Smecta plus Ribavirin 93 55% were cure treat at six days;and 75 01% were in Ribavirin.The difference among two groups had statistical significance( P =0 038).By test of sick course,the mean time of the recovery from an illness was 3 1±1 26days in Smecta plus Ribavirin;that was 5 2±0 93days in Ribavirin;The difference among two groups was remarkable all( P =0 011).Conclusion Compared with contrast group,the use of Smecta in infants with diarrhea for NLV infection has striking effect,and guide clinical medicine has important meaning.
出处
《福建医药杂志》
CAS
2003年第4期17-18,共2页
Fujian Medical Journal
基金
福建省自然科学基金 ( C0 110 0 0 8)
福建省教育厅 ( JA0 10 2 1)资助项目
