摘要
目的:研究原发性肝癌患者血浆凝血酶原的变化,并探讨其诊断价值。方法:原发性肝癌病人15例,并设健康成人对照组30例。用Ecarin-发色底物法检测其凝血酶原总量与吸附后凝血酶原量,用一期法测定PT。结果:患者PT、凝血酶原总量与吸附后凝血酶原量均高于对照组,后者在原发性肝癌的阳性率为93.33％(14/15),如以超过正常值一倍为诊断值,其阳性率为73.33％(11/15)。结论:原发性肝癌患者血浆中异常凝血酶原量明显增多,可作为诊断标志物之一。
Objective: To study the change of prothrombin in plasma on prtients with primary hepatoma and set up the diagnostic value. Methods:Primary hepatoma patients 15 cases and control health adult 30 cases.The PT with one step method, total prothrombin and after absorb prothrombin were deaterminated with Ecarin-chromogenic pep-tide substrate method . Results: All three data significant higher in patients than in controls. After absorb prothrombin positive rate in patients were 93.33%(14/15) diagnostic value are normal value two fold. The diagnostic positive rate were 73.33% ( 11/15) . Conclusion: The absorb prothrombin (abnormal prothrombin)obvious increase in plasma of patients with primary hepatoma and make for a diagnostic mark.
出处
《血栓与止血学》
2003年第3期111-112,共2页
Chinese Journal of Thrombosis and Hemostasis
