摘要
目的对比分析声脉冲辐射力成像(ARFI)技术和瞬时弹性成像(TE)技术诊断慢性乙型肝炎(CHB)肝纤维化的临床应用价值。方法应用ARFI和TE技术检测189例CHB患者的肝脏弹性,以病理结果为金标准,比较ARFI和TE技术对不同肝纤维化分期的诊断价值。结果 ARFI技术检测成功率为100%,TE技术检测成功率为95.23%,差异有统计学意义(P=0.007)。ARFI和TE测值均与肝纤维化分期呈正相关,相关系数分别为0.60和0.63(P<0.01)。ARFI和TE技术诊断肝纤维化S2期的ROC曲线下面积分别为0.764和0.813(P=0.302);S3期的ROC曲线下面积分别为0.852和0.852(P=1.000);S4期的ROC曲线下面积分别为0.825和0.799(P=0.655)。结论 ARFI和TE技术在无创诊断CHB肝纤维化程度方面具有相似的诊断价值,但ARFI技术成功率高,适用范围广,更具有临床应用优势。
Objective To compare and analyze the clinical practical values of acoustic radiation force impulse(ARFI) imaging and transient elastography(TE) on diagnosing liver fibrosis in patients with chronic hepatitis B(CHB).Methods Liver elasticity were measured on 189 patients with CHB using ARFI and TE. The diagnostic values of ARFI and TE on different stages of liver fibrosis were compared using pathology results as golden standard.Results The success rate of ARFI was 100%,and that of TE was 95.23%(P =0.007).ARFI and TE correlated positively with histological fibrosis,and correlation coefficients were 0.60 and 0.63(P <0.01). The areas under ROC curve of ARFI imagining and TE on diagnosing liver fibrosis S2 stage were 0.764 and 0.813(P=0.302),those on S3 stage were 0.852 and 0.852(P=1.000),and those on S4 stage were 0.825 and 0.799(P=0.655).Conclusion ARFI and TE has similar diagnositic values on liver fibrosis in CHB,but ARFI has higher success rate,wider application range,and more clinical application advantages.
出处
《临床超声医学杂志》
2016年第1期21-24,共4页
Journal of Clinical Ultrasound in Medicine
关键词
声脉冲辐射力成像
瞬时弹性成像
乙型肝炎
慢性
肝纤维化
Acoustic radiation force impulse imaging
Transient elastography
Hepatitis B,chronic
Liver fibrosis
