摘要
目的 探讨 β2 -肾上腺素能受体兴奋剂安宝抑制子宫收缩 ,治疗早产的临床效果。方法 对 91例先兆早产孕妇随机分为两组 ,分别静脉滴注安宝或硫酸镁。采用达到有效宫缩的最低浓度 ,适时停药 ,病情反复则间歇多次应用。结果 安宝首次用药达有效抑制宫缩的显效时间为 2h 40min ;延长孕期 2 9.3 4d ;足月分娩率 71.74% ;均极显著优于硫酸镁组 (P分别 <0 .0 0 1 0 .0 1 0 .0 1)。尚未发现严重毒副反应。结论 安宝抑制宫缩作用强显效快 ,治疗早产安全有效。
Objective to investigate the treatment of preterm labor with the β adrenergic agonist anpo.Methods 91women with preterm labor were randomly assigned to intravenous infusion of Anpo or magnesium sulfate treatment.Using minimal effective dosage for inhibition of uterine activity,terminating therapy on time,and repeating the i.v.infusion if contraction restarted were the strategy for treatment.Anpo was significantly more effective both in the treating period for suppression of contraction(2h40min)and prolongation of gestation(29.34d) than that of the magnesium sulfate(P<0.001,0.01and 0.01 respectively),and had a term labor of 71.74%.There was no serious cardiac and pulmonary complications in the Anpo group.Conclusion The present study has shown that Anpo as a tocolytic agent is highly effective for the management of preterm labor and relative safe for mother and fetus.
出处
《河南医药信息》
2003年第3期4-4,6,共2页
Henan Medical Information
