摘要
目的 探讨高甘油三酯血症与急性胰腺炎 (AP)的关系。方法 收集 1998年 4月至2 0 0 0年 10月 ,我院部分住院AP患者 41例资料。检测血清甘油三酯 (TG)≥ 11.3mmol/L的AP13例 (Ⅰ组 ) ,其中胆源性 8例 (61.5 % ) ,非胆源性 5例 (3 8.5 % ) ;TG <11.3mmol/L的AP2 8例 (Ⅱ组 ) ,胆源性 19例 (4 7.3 % ) ,非胆源性 9例 (5 2 .7% )。对两组的RANSON积分 ,并发症发生率和转氨酶水平进行比较 ,并且对TG值和RANSON积分进行相关分析。结果 Ⅰ组与Ⅱ组相比 ,RAN SON积分 ,并发症发生率和转氨酶水平显著性增高 (P <0 .0 5 )。 41例病患的TG值和RANSON积分之间存在直线相关 (P <0 .0 1) ,Ⅰ组TG值和RANSON积分之间存在直线相关关系 (P <0 .0 1) ,该组中 8例胆源性病例也存在直线相关关系 (P <0 .0 1) ,Ⅱ组TG值和RANSON积分之间无直线相关关系 (P >0 .0 5 ) ,其中 19例胆源性病例无直线相关关系 (P >0 .0 5 )。结论 高甘油三酯血症与AP的关系密切 ,血清甘油三酯水平与AP的病变程度呈正相关 ,合并高甘油三酯血症的AP其并发症的发生率有明显的增高 。
Objective To evaluate the relationship between hypertriglyceridemia and acute pancreatitis.Methods Data was analyzed from 41 patients with acute pancreatits from Apr.1998 to Oct.2000 in our hospital.Of the 13 patients(GroupⅠ) with plasma TG level being higher than 11.3 mmol/L, 8 accompanied with gallstone(61.5%)and 5 without gallstone(38.5%)of the 28 patients (GroupⅡ) with plasma TG level being lower than 11.3 mmol/L,19 accompanied with gallstone(47.3%)and 9 without gallstone(52.7%)RANSON score,morbidity of complications and the level of ALT and AST were compared between two groaps.The correlation between TG and RANSON score was analysed.Results There were significant difference between the two groups on RANSON score,morbidity of complications and level of ALT and AST(P<0.05).And the correlation between TG and RANSON score in all the patients, in patients of GroupⅠand in 8 patients with acute biliary pancreatitis of GroupⅠ were significant(P<0.01).However,the correlation in patients of GroupⅡand in 19 patients with acute biliary pancreatitis of GroupⅡwas not significant(P>0.05).Conclusion There is an close relationship between hypertriglyceridemia and acute pancreatitis,the high level of plasma TG plags a key a role in acute pancreatitis,patients with acute pancreatitis with hypertriglyceridemia are more likely to have higher morbidity of complications and liver function aggravating.
出处
《临床外科杂志》
2003年第2期76-78,共3页
Journal of Clinical Surgery
