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冠状动脉旁路移植术瞬时测血流量技术的临床应用 被引量:12

Transit time flow measurement in coronary surgery
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摘要 目的 总结瞬时测血流量 (TTFM)技术在冠状动脉旁路移植术 (CABG)中的应用经验 ,探讨异常血管桥瞬时血流量技术参数特点、发生原因及处理方法。方法  2 0 0 1年 9月至 2 0 0 2年 5月 ,连续对5 0例不停跳冠状动脉旁路移植及 40例常规体外循环下旁路移植者进行血管桥血流量测定 ,随机 30例进行左侧乳内动脉 (LIMA)血流量测定。结果  30例LIMA离断后TTFM参数 :平均血流 (42 9± 33 0 )ml min ,弹力指数 (PI)值 1 0 0± 0 6 4,波形曲线为收缩期、舒张期双向血流 ,收缩期为主 ,实际平均血流为(37 4± 2 8 8)ml min ,相关系数为 0 98。 90例冠状动脉旁路移植TTFM参数 :LIMA到左前降支 (LAD)平均流量 (2 9 9± 9 5 )ml min ,平均PI值 2 47± 0 88。大隐静脉或桡动脉到回旋支系统平均流量 (33 7±17 5 )ml min ,PI值 4 0± 1 9;到右冠状动脉系统 ,平均流量 (31 5± 19 2 )ml min ,PI值 2 6± 1 3 ;到前降支及回旋支系统为双向血流 ,血流以舒张期为主 ,收缩期可形成负值 ;到右冠状动脉系统 ,收缩及舒张期为双向灌注 ,较少出现负值。TTFM技术提示 ,2 87支血管桥中有质量问题血管桥 6支 ,均手术证实并加以矫正。 90例病人均无围术期心肌梗死及其它严重并发症 ,无死亡。随访 2~ 10个月 。 Objective: To review the experience of using the transit time flow measurement(TTFM) in coronary artery bypass grafting(CABG). Methods: From Sept.2001 to May, 2002,90 cases underwent CABG. Among them, 40 cases with off-pump beating heart (OPCAB) and 50 with conventional coronary bypass grafting. All graft patency were verified intraoperatinlly with TTFM. The flow value of left internal mammary artery (LIMA) in 30 cases was also detected by the same way before grafting to left anterior descending (LAD). Results: There was no operative death and severe complications. The mean flow value of LIMA in 30 cases was (42.9±33.0)ml/min. The actual blood flow value, measured simultaneously by exsanguination was (37.4±28.8)ml/min. Excellent correlation was demonstrated. The mean pulsatility index value (PI) was 1.00±0.04. The flow curve showed both diastolic and systolic filling. The mean flow value of LIMA to LAD, saphenous vein graft (SVG) or radial artery (RA) to circumflex coronary artery (LCX) or diagonal (D), SVG or RA to right coronary artery (RCA) or post anterior artery (PDA) were (29.9±9.5)ml/min, (33.7±17.5)ml/min and (31.5±19.2)ml/min. The PI values were 2.47±0.88, 4.00±1.90 and 2.60±1.30, respectively. The typical flow curve was shown in all LIMA to LAD, and SVG (or RA) to LCX (or D). Blood flow filling was mainly during diastole with minimal systolic peaks during the isovolumetric ventricular contraction. SVG or RA to RCA presents a particular flow pattern characterized by a dual filling. 6 grafts were revised basing on unsatisfied flow curves, PI, and the mean flow or all of them. Significant technical error such as conduit kinking, stenosis of distal anastomosis was found. Conclusion: The patency of graft in CABG can be verified in intraoperatively by use of TTFM. The decision of checking or revising a graft can be made basing on parameters acquired from the TTFM device. To correctly analyze the parameters warrants good clinical results.
出处 《中华胸心血管外科杂志》 CSCD 北大核心 2003年第1期29-32,共4页 Chinese Journal of Thoracic and Cardiovascular Surgery
关键词 冠状动脉疾病 冠状动脉分流术 瞬时血流测量 Coronary disease Coronary artery bypass Transit time flow measurement
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