摘要
目的 :探讨介入技术治疗缺血性脑血管疾病的近远期疗效和安全性。方法 :从我院神经内科2013年8月~2014年3月期间收治的确诊为短暂性脑缺血发作的142例患者中,选择符合诊断标准和血管内支架植入标准的患者120例,随机分为治疗组和对照组,每组各60例。治疗组采用药物治疗并行介入治疗,对照组单纯药物治疗,两组患者30天,半年,一年定期随访,记录随访患者的病变血管(l Vs),神经功能缺损评分(NIHSS),脑梗死复发率、病死率等情况。结果 :两组患者治疗前病变血管对比差异无统计学意义;治疗组术前及术后12个月病变血管对比,差异有统计学意义;对照组治疗前和治疗12个月病变血管对比差异无统计学意义。治疗组术后一年与对照组治疗一年后,病变血管对比差异有统计学意义。神经功能缺损评分(NIHSS)评分比较,治疗前两组NIHSS评分比较,差异无统计学意义;治疗组NIHSS评分在术后30天、6个月、12个月均有显著改善,对照组和治疗后在相同时间点NIHSS评分比较,差异均有统计学意义。两组患者随访期间缺血性脑血管病发生率、病死率比较,治疗组与对照组比较差异无统计学意义。结论 :血管内支架成形术是治疗缺血性脑血管病的安全有效方法,并能促进患者的神经功能恢复,值得在临床应用推广。
Objective To investigate the efficacy of interventional treatment of ischemic cerebral vascular disease; to observe the incidence of its complications.Methods According to the diagnostic criteria of ischemic cerebrovascular disease were divided into the treatment group of 51 cases,63 cases in the control group,all the patients were followed up for 12 months,recorded during the follow-up of vascular lesions in Vs,the recurrence rate of cerebral infarction,neural function defect score NIHSS.Results The two groups of patients before treatment had no difference in vascular lesions(Vs).In treatment group before and after surgery 12 months,vascular lesions comparison,the difference was statistically significant.Control group before treatment and after surgery 12 months between the vascular lesions comparison was not statistically significant.The patients in the treatment group and the control group after one year,there were statistically significant differences in Vs between vascular lesions.Comparison of Vs in the treatment group and control group after treatment 12 months,the difference was statistically significant.NIHSS score was better than simple drug treatment group.A simple drug treatment group were followed up 9 cases of ischemic cerebral vascular disease occurred 12 months(14.29%); the two groups,the difference had no statistically significant.Conclusion Endovascular stent angioplasty is a safe and effective method for the treatment of ischemic cerebrovascular disease,and can promote the recovery of neurological function,worthy of clinical application..
出处
《湖南师范大学学报（医学版）》
2015年第3期62-64,共3页
Journal of Hunan Normal University(Medical Sciences)
关键词
缺血性脑血管病
动脉狭窄
支架成形术
脑梗死
ischemic cerebrovascular disease
carotid artery stenosis
stent
cerebral infarction
