摘要
目的探讨胃宝方联合穴位贴在脾胃气虚兼夹血瘀型慢性胃炎(CG)患者中的治疗效果。方法选取2022年1月至2024年12月宁德市中医院脾胃病科收治的120例脾胃气虚兼夹血瘀型CG患者作为研究对象,按照随机数字表法分为对照组与观察组,每组60例。对照组采用常规西药治疗,观察组加用胃宝方联合穴位贴治疗。比较两组患者的临床治疗有效率、症状缓解时间、胃肠道激素[胃泌素(GAS)、胃动素(MOT)]、炎症因子[白细胞介素-8(IL-8)、白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)]。结果治疗2周后,观察组总有效率高于对照组,各项症状缓解时间均短于对照组,GAS、MOT、IL-8、IL-6、TNF-α均低于对照组,差异有统计学意义(P<0.05)。结论对脾胃气虚兼夹血瘀型CG患者予以胃宝方联合穴位贴治疗,可以提高整体疗效,加速不适症状缓解,调节胃肠道激素表达,减轻炎症反应。
Objective To explore the therapeutic effect of Weibao Fang combined with acupoint paste in patients with chronic gastritis(CG)of spleen-stomach qi deficiency and blood stasis type.Methods A total of 120 patients with CG of spleen-stomach qi deficiency and blood stasis type admitted to the Department of Spleen and Stomach Diseases of Traditional Chinese Medicine Hospital of Ningde from January 2022 to December 2024 were selected as the research objects,they were divided into the control group and the observation group according to the random number table method,with 60 cases in each group.The control group was treated with conventional Western medicine,while the observation group was additionally treated with the Weibao Fang combined with acupoint paste.The clinical treatment effective rate,symptom relief time,gastrointestinal hormones(gastrin[GAS],motilin[MOT]),inflammatory factors(interleukin-8[IL-8],interleukin-6[IL-6],tumor necrosis factor-α[TNF-α])of the two groups of patients were compared.Results After 2 weeks of treatment,the total effective rate of the observation group was higher than that of the control group,the relief time of each symptom were shorter than those of the control group,and the GAS,MOT,IL-8,IL-6,and TNF-αwere all lower than those of the control group,the differences were statistically significant(P<0.05).Conclusion For CG patients with spleen-stomach qi deficiency and blood stasis type,the treatment of Weibao Fang combined with acupoint paste can improve the overall therapeutic effect,accelerate the relief of discomfort symptoms,regulate the expression of gastrointestinal hormones,and reduce inflammatory responses.
作者
陈巧娟
高乾良
叶文彬
CHEN Qiaojuan;GAO Qianliang;YE Wenbin(Department of Spleen and Stomach Diseases,Traditional Chinese Medicine Hospital of Ningde,Fujian Province,Ningde 352100,China;Department of Traditional Chinese Medicine,Fuzhou Xiao Zhi'an Hospital of Traditional Chinese Medicine Surgery,Fujian Province,Fuzhou 350001,China)
出处
《中国当代医药》
2025年第24期106-109,共4页
China Modern Medicine
关键词
胃宝方
穴位贴
脾胃
气虚血瘀型
慢性胃炎
Weibao Fang
Acupoint paste
Spleen and stomach
Qi deficiency and blood stasis type
Chronic gastritis
