摘要
目的分析2007—2022年唐山市布鲁菌病(简称布病)的流行特征及疾病负担情况,探究唐山市疾病负担的社会经济影响因素,为进一步优化布病防治策略及合理配置医疗资源提供理论基础。方法根据2007—2022年唐山市布病监测数据,分别计算布病发病率、健康寿命损失年(years lived with disability,YLD)、标化YLD率、间接经济负担等指标,评估布病健康负担和经济负担情况;采用Joinpoint回归分析布病的健康负担随时间及年龄变化趋势,采用广义线性模型分析其疾病负担的社会经济影响因素。结果2007—2022年唐山市共报告布病3949例,年均发病率3.23/10万;男性多于女性,50~<60岁组发病数最多,迁安、滦南、乐亭等东部地区发病率较高;16年间布病YLD损失共计118.47人年,YLD率共计0.01529‰,50~<60岁组YLD和YLD率最高(36人年,0.00370‰);男性(88.71人年,0.02224‰)高于女性(29.76人年,0.00790‰),东部地区(75.48人年,0.00200‰)高于中心城区(11.49人年,0.00043‰)和西部地区(31.50人年,0.00062‰);健康负担和间接经济负担呈先上升后下降趋势,与发病率趋势基本一致;30岁以上人群、东部地区间接经济负担较重;医疗机构数、卫生技术人员数、农村人均可支配收入、羊肉产量、牛肉产量、奶产量是疾病负担的社会经济影响因素。结论唐山市东部地区、中老年男性的布病发病率较高,且健康负担和经济负担较重,相关地区应建立多部门疫情互通机制,加强牲畜检疫和流通监管,加大宣传教育力度,合理配置医疗卫生和专业人才资源,进一步降低唐山市布病的健康负担和经济损失。
Objective To analyze the epidemic characteristics and disease burden of brucellosis in Tangshan City from 2007 to 2022,explore the socioeconomic determinants of that burden,and provide a theoretical basis for further optimizing the prevention and control strategies of brucellosis and rationally allocating medical resources.Methods Based on monitoring data of brucellosis in Tangshan City from 2007 to 2022,the incidence rate,years lived with disability(YLD),standardized YLD rate,and indirect economic burden were calculated to assess the change of the disease burden.Joinpoint regression analysis was used to examine the trends in the health burden of brucellosis over time and by age.A generalized linear model was used to explore the socioeconomic factors associated with the burden.Results A total of 3949 cases of brucellosis were reported from 2007 to 2022,yielding an average incidence rate of 3.23/10 million.Incidence was higher in males than in females and peaked in the 50-<60-year age group.The incidence rate was higher in the eastern areas such as Qian'an,Luannan,and Laoting.Over the 16 years,brucellosis caused 118.47 person-years of YLDs,corresponding to an overall YLD rate of 0.01529‰.The 50-<60-year group had the greatest YLDs and YLD rate(36 person-years,0.00370‰).Males(88.71 person-years,0.02224‰)bore a heavier burden than females(29.76 person-years,0.00790‰),and the eastern region(75.48 person-years,0.00200‰)exceeded the central urban area(11.49 person-years,0.00043‰)and the western region(31.50 person-years,0.00062‰).Both the health burden and the indirect economic burden first rose and then declined,mirroring the incidence trend.Adults aged 30 years and older,and residents of the eastern region,carried the greatest indirect economic burden.The number of medical institutions and health manpower,rural per capita disposable income,mutton output,beef output,and milk output were identified as significant socioeconomic determinants of brucellosis burden.Conclusion Middle-aged and older men in the eastern regions of Tangshan experience the highest incidence and greatest health and economic burden of brucellosis.Local authorities should establish intersectoral information-sharing mechanisms,strengthen livestock quarantine and supply-chain supervision,enhance public education,and allocate medical resources and facilities rationally to further reduce the health and economic impact of brucellosis in Tangshan.
作者
高雯
解光越
柳建强
张岭
裴婕
刘向博
刘弘历
刘铮
GAO Wen;XIE Guangyue;LIU Jianqiang;ZHANG Ling;PEI Jie;LIU Xiangbo;LIU Hongli;LIU Zheng(Institute for the Prevention and control of infectious diseases,Tangshan City Center for Disease Control and Prevention,Tangshan,Hebei 063000,China;Tangshan Worker's Hospital,Tangshan,Hebei 063000,China)
出处
《中国热带医学》
北大核心
2025年第8期1069-1074,共6页
China Tropical Medicine
作者简介
高雯(1982-),女,硕士,主任医师,研究方向:传染病防治。E-mail:tangshancrb@126.com。
