摘要
用荧光法测定111例正常人动脉血(其中23例同时测定静脉血)及9例闭塞性肺动脉高压病人动、静脉血中血管紧张素转换酶(ACE)活力。正常人动脉血中ACE活力高于静脉血(P<0.05);闭塞性肺动脉高压病人动、静脉血中ACE活力分别高于正常人动、静脉血(P<0.05)。
The authors used modified fluorimetric method to measure arterial and venous serum angiotensin-converting enzyme(ACE)activity in normal adults and patients with obliterative pulmonary hypertension.The ACE was found higher in arterial than in venous blood in normal adults(P<0.05).The ACE activity in patients with obliterative pulmonary hypertension was higher both in arterial and venous blood than that of normal adults(both P<0.05).Results suggested that lung endothelial cells released ACE into blood under normal condition and pulmonary hyperten-sion stimulated these to release more ACE.
作者
孙仁宇
严仪昭
张宏
程显声
刘晓波
Sun Renyu(Institute of Basic Medical Sciences,Academiae Medicinae Sinicae,Beijing)
出处
《中国医学科学院学报》
1988年第1期36-39,共4页
Acta Academiae Medicinae Sinicae
关键词
血管紧张素转换酶
闭塞性肺动脉高压
angiotensin converting enzyme(ACE)
obliterative pulmonary hypertension
