摘要
目的分析保留肋间神经的改良根治术治疗乳腺癌患者的临床效果。方法选取2019年1月至2023年12月收治的60例乳腺癌患者为研究对象,将其随机分为不保留组(采用不保留肋间神经的改良根治术治疗)和保留组(采用保留肋间神经的改良根治术治疗),每组30例。比较两组的治疗效果。结果两组的淋巴结清扫个数比较,差异无统计学意义(P>0.05);保留组的手术时长长于不保留组,术中出血量少于不保留组,住院时长短于不保留组,差异具有统计学意义(P<0.05)。保留组的术后不良事件总发生率低于不保留组(P<0.05);两组的术后半年复发率比较,差异无统计学意义(P>0.05)。术后3 h,两组的视觉模拟评分法(VAS)评分比较,差异无统计学意义(P>0.05);术后24 h、第3天、第5天,保留组的VAS评分显著低于不保留组(P<0.05)。术后,保留组的手术侧肩关节背伸、前屈、内收、外展、内旋、外旋、上举活动度高于不保留组(P<0.05)。术后,保留组的美国加州大学洛杉矶分校肩关节评分(UCLA)、乳腺癌患者生命质量测定量表(FACT-B)评分高于不保留组(P<0.05)。结论保留肋间神经的改良根治术治疗乳腺癌患者可取得理想手术效果,且预后较佳。
Objective To analyze the clinical effect of modified radical mastectomy with preservation of intercostal nerve in the treatment of patients with breast cancer.Methods A total of 60 patients with breast cancer admitted from January 2019 to December 2023 were selected as the research objects.The patients were randomly divided into non-reserved group(treated with modified radical mastectomy without preserving intercostal nerve)and reserved group(treated with modified radical mastectomy with preserving intercostal nerve),with 30 cases in each group.The therapeutic effects of the two groups were compared.Results There was no significant difference in the number of lymph node dissection between the two groups(P>0.05);the operation time of the reserved group was longer than that of the non-reserved group,the intraoperative blood loss was less than that of the non-reserved group,the hospitalization time was shorter than that of the non-reserved group,and the differences were statistically significant(P<0.05).The total incidence of postoperative adverse events in the reserved group was lower than that in the non-reserved group(P<0.05);there was no significant difference in the recurrence rate between the two groups after half a year(P>0.05).At 3 h after operation,there was no significant difference in Visual Analogue Scale(VAS)score between the two groups(P>0.05);at 24 h,3rd and 5th after operation,the VAS score of the reserved group was significantly lower than that of the non-reserved group(P<0.05).After operation,the range of motion of dorsal extension,flexion,adduction,abduction,internal rotation,external rotation and lifting of shoulder joint on the operation side in the reserved group were higher than those in the non-reserved group(P<0.05).After operation,the University of California at Los Angeles Shoulder Scores(UCLA)and Functional Assessment of Cancer Therapy-Breast(FACT-B)scores in the reserved group were higher than those in the non-reserved group(P<0.05).Conclusion The modified radical mastectomy with preservation of intercostal nerve for breast cancer patients can achieve ideal surgical results and has a better prognosis.
作者
吴骥
邱兴
吴研哲
柏建印
吴建强
WU Ji;QIU Xing;WU Yanzhe;BO Jianyin;WU Jianqiang(General Surgery Department,Nanjing Drum Tower Hospital Group Suqian Hospital/the Affiliated Suqian Hospital of Xuzhou Medical University,Suqian 223800;Clinical Medicine Department,School of Basic Medicine Sciences,Chengde Medical University,Chengde 067000,China)
出处
《临床医学研究与实践》
2025年第25期94-97,共4页
Clinical Research and Practice
关键词
乳腺癌
保留肋间神经
改良根治术
肩关节功能
手术预后
breast cancer
preservation of intercostal nerve
modified radical mastectomy
shoulder joint function
surgical prognosis
作者简介
吴骥(1978-),男,主任医师,硕士。研究方向:乳腺癌的临床及基础研究;通讯作者:吴建强,E-mail:WJQ-10@163.com.
