摘要
目的对比经胫前静脉入路导管溶栓术、腘静脉置管溶栓术治疗急性下肢深静脉血栓形成(DVT)的效果。方法采用回顾性研究方式,选取2021年1月至2024年6月该院收治的急性下肢DVT患者140例,依据不同溶栓入路分为胫前静脉组(69例)和腘静脉组(71例)。胫前静脉组行经胫前静脉入路导管溶栓术,腘静脉组行腘静脉置管溶栓术,比较2组疗效(尿激酶用量、溶栓时间等)、血栓清除率、并发症发生率、消肿状况、静脉通畅度等。结果2组患者尿激酶总量、溶栓时间,以及治疗后大腿周径差、大腿消肿率、血栓清除率比较,差异均无统计学意义(P>0.05);腘静脉组患者治疗后小腿周径差明显低于胫前静脉组[(0.72±0.20)cm vs.(1.34±0.61)cm],小腿消肿率明显低于胫前静脉组[(74.28±6.52)%vs.(85.51±7.01)%],静脉通畅评分[(1.10±0.36)分vs.(0.95±0.30)分]、并发症发生率[35.21%(25/71)vs.11.59%(8/69)]均明显高于胫前静脉组,差异均有统计学意义(P<0.05)。结论与腘静脉置管溶栓术比较,胫前静脉入路导管溶栓术治疗急性下肢DVT的效果更佳,可减少并发症,加快肿胀消退。
Objective To compare the effects of catheter embolization via the anterior tibial vein and popliteal vein catheterization thrombolysis for the treatment of acute deep vein thrombosis(DVT)in the lower extremities.Methods A retrospective study was conducted.A total of 140 patients with acute lower extremity DVT admitted to the hospital from January 2021 to June 2024 were selected and divided into the anterior tibial vein group(69 cases)and the popliteal vein group(71 cases)according to different thrombolytic approaches.The anterior tibial vein group underwent catheter embolization via the anterior tibial vein approach,while the popliteal vein group underwent popliteal vein catheterization thrombolysis.The therapeutic effects(dosage of urokinase,thrombolysis days,etc.),thrombus clearance rate,complication rate,swelling reduction status,and venous patency were compared between the two groups.Results The total amount of urokinase and thrombolytic time were recorded in the two groups.There was no significant difference in thigh circumference difference,thigh swelling rate,and thrombus clearance rate between the two groups after treatment(P>0.05).After treatment,the calf circumference difference in the popliteal vein group was significantly lower than that in the anterior tibial vein group[(0.72±0.20)cm vs.(1.34±0.61)cm],the calf swelling rate wa s significantly lower than that in the anterior tibial vein group[(74.28±6.52)% vs.(85.51±7.01)%],the venous patency score[(1.10±0.36)points vs.(0.95±0.30)points]and the incidence of complications were significantly higher than those in the anterior tibial vein group[35.21%(25/71)vs.11.59%(8/69)],and the differences were statistically significant(P<0.05).Conclusion Compared with popliteal vein catheterization thrombolysis,catheter embolization via anterior tibial vein has better therapeutic effect on acute lower limb DVT,can reduce complications,and accelerate the regression of swelling.
作者
薛亚斌
沈冬冬
张哲
XUE Yabin;SHEN Dongdong;ZHANG Zhe(The Third Department of Vascular Surgery,The Second People's Hospital of Jiaozuo,Jiaozuo,Henan 454000,China)
出处
《现代医药卫生》
2025年第8期1846-1849,1854,共5页
Journal of Modern Medicine & Health
关键词
导管接触式溶栓
下肢
深静脉血栓形成
胫前静脉
腘静脉
Catheter-contact thrombolysis
Lower limb
Deep venous thrombosis
Anterior tibial vein
Popliteal vein
作者简介
薛亚斌(1990-),硕士研究生,主治医师,主要从事下肢静脉曲张研究。
