摘要
目的:口腔按摩是一种通过轻柔刺激口腔肌肉和神经,帮助改善吸吮、吞咽和呼吸协调的干预方法。本研究旨在探讨口腔按摩对极低出生体重儿支气管肺发育不良(bronchopulmonary dysplasia,BPD)的影响。方法:回顾性收集2022年1月至2023年1月南京医科大学附属儿童医院新生儿科收治的极低出生体重儿,根据纳入和排除标准筛选出92例,其中口腔按摩组48例、非口腔按摩组44例。收集出生资料、喂养情况、肺泡表面活性物质使用情况、机械通气及住院时间,进行单变量、多变量统计分析。结果:口腔按摩组喂养不耐受发生率较低,达到经口喂养日龄较小,而且住院时间更短(均P<0.05)。口腔按摩组BPD及中-重度BPD发生率较低,机械通气时间更短(均P<0.05)。口腔按摩可减少BPD的发生,其粗略OR值为0.159(95%CI 0.048~0.525),校正OR值为0.099(95%CI 0.016~0.613)。结论:口腔按摩不仅可改善极低出生体重儿喂养困难,降低喂养不耐受,还可能有助于减少极低出生体重儿BPD发生,改善其临床结局,值得推广。
Objective:Oral massage is an intervention that gently stimulates oral muscles and nerves to improve coordination of sucking,swallowing,and breathing.This study aims to investigate the effect of oral massage on bronchopulmonary dysplasia(BPD)in very low birth weight infants.Methods:A retrospective review was conducted of very low birth weight infants admitted to the Department of Neonatology,Children’s Hospital of Nanjing Medical University,between January 2022 and January 2023.A total of ninety-two infants were screened according to inclusion and exclusion criteria,with 48 in the oral massage group and 44 in the non-oral massage group.Perinatal data,feeding status,use of pulmonary surfactant,duration of mechanical ventilation,and length of hospital stay were collected.Both univariate and multivariate statistical analyses were performed.Results:Compared with the non-oral massage group,the oral massage group had a lower incidence of feeding intolerance,achieved oral feeding at an earlier age,and had a shorter hospital stay(all P<0.05).The incidence of BPD and moderate-to-severe BPD was significantly lower in the oral massage group,as was the duration of mechanical ventilation(all P<0.05).Oral massage reduced the risk of BPD,with a crude OR of 0.159(95%CI 0.048 to 0.525)and an adjusted OR of 0.099(95%CI 0.016 to 0.613).Conclusion:Oral massage not only alleviates feeding difficulties and reduces feeding intolerance in very low birth weight infants but may also help decrease the incidence of BPD and improve clinical outcomes.This approach is worthy of clinical promotion.
作者
徐梦娟
沈飞
童幸
石路
张方平
戎惠
XU Mengjuan;SHEN Fei;TONG Xing;SHI Lu;ZHANG Fangping;RONG Hui(Department of Neonatology,Children’Hospital of Nanjing Medical University,Nanjing 210008,China)
出处
《临床与病理杂志》
2025年第5期581-587,共7页
Journal of Clinical and Pathological Research
作者简介
第一作者:徐梦娟,Email:1191865444@qq.com,ORCID:0009-0003-8102-0301;通信作者:戎惠,Email:2316811759@qq.com,ORCID:0009-0003-9107-0432。
